Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GABRP | O00591 | 2/20 | 0.38 |
| ▸ | GABRD | O14764 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.38 |
| ▸ | GABRE | P78334 | 2/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2201846 | 0.84 | TAAR1 (0.52) | LMNANOS3NOS2KDM4EGABRP | |
| SCHEMBL23377250 | 0.82 | SLC2A1 (0.39) | LMNANOS3NOS2GABRPGABRD | |
| SCHEMBL8697456 | 0.81 | GABRP (0.38) | NOS3NOS2KDM4EGABRPGABRD | |
| SCHEMBL23815821 | 0.80 | NOS3 (0.45) | NOS3NOS2KDM4EGABRPGABRD | |
| SCHEMBL12352043 | 0.78 | LMNA (0.47) | LMNAALOX15TDP1HDAC1HDAC6 | |
| SCHEMBL20342450 | 0.78 | LMNA (0.47) | LMNAALOX15TDP1HDAC1HDAC6 | |
| SCHEMBL2677573 | 0.78 | ALDH1A1 (0.46) | NOS3NOS2KDM4EGABRPGABRD | |
| SCHEMBL6469008 | 0.78 | NOS3 (0.46) | NOS3NOS2KDM4EGABRPGABRD | |
| SCHEMBL23655471 | 0.77 | NOS3 (0.44) | NOS3NOS2KDM4EGABRPGABRD | |
| SCHEMBL8924164 | 0.77 | LMNA (0.45) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108349960-B | Nostoc compounds and conjugates, their preparation and their therapeutic use | 赛诺菲 | 2022-05-27 | — | — | CN | disclosed |
| EP-3371179-A1 | NOVEL CRYPTOPHYCIN COMPOUNDS AND CONJUGATES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | SANOFI (FR) | 2018-09-12 | — | — | EP | disclosed |
| CN-108349960-A | New nostoc element compound and conjugate, their preparation and their therapeutical uses | 赛诺菲 | 2018-07-31 | — | — | CN | disclosed |
| WO-2017076998-A1 | NOVEL CRYPTOPHYCIN COMPOUNDS AND CONJUGATES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | SANOFI (FR) | 2017-05-11 | — | — | WO | disclosed |
| US-5003069-A | Chichibabin reaction | REILLY INDUSTRIES, INC. (US) | 1991-03-26 | — | — | US | disclosed |
| EP-0098684-A2 | Modified chichibabin reaction, and novel pyridine derivatives | REILLY INDUSTRIES, INC. (US) | 1984-01-18 | — | — | EP | disclosed |