Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.36 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28634617 | 0.74 | CA2 (0.41) | BAZ2BHTTHDAC2PDE4BPLK1 | |
| SCHEMBL22017871 | 0.73 | MEN1 (0.48) | KMT2AALDH1A1 | |
| SCHEMBL21431458 | 0.69 | HDAC1 (0.38) | HDAC1JAK3ALDH1A1 | |
| SCHEMBL22018668 | 0.68 | CA2 (0.50) | HDAC2GSK3BCLK4LMNAALDH1A1 | |
| SCHEMBL22018050 | 0.68 | ALDH1A1 (0.47) | KMT2AHDAC2ALDH1A1HPGD | |
| SCHEMBL3223294 | 0.65 | CHRNB2 (0.65) | FGFR1FGFR2FGFR4FGFR3CHRNB2 | |
| SCHEMBL22018290 | 0.64 | CA12 (0.41) | KMT2AMAPK14LMNAALDH1A1HPGD | |
| SCHEMBL29434886 | 0.63 | HNF4A (0.66) | FGFR1FGFR2FGFR4FGFR3CHRNB2 | |
| SCHEMBL22124840 | 0.63 | ALDH1A1 (0.38) | KMT2AALDH1A1HPGDPABPC1EIF4H | |
| SCHEMBL15472559 | 0.62 | CHRNB2 (0.56) | FGFR1FGFR2FGFR4FGFR3CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099367-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2020-05-22 | — | — | WO | disclosed |