Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22018967 | 0.81 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2LMNAKMT2AKDM4E | |
| SCHEMBL15983357 | 0.80 | TSHR (0.41) | ALDH1A1SMN1; SMN2LMNAKMT2ACYP3A4 | |
| SCHEMBL22018972 | 0.80 | KMT2A (0.50) | ALDH1A1SMN1; SMN2LMNAKMT2ACYP3A4 | |
| SCHEMBL22019400 | 0.79 | LRRK2 (0.57) | ALDH1A1SMN1; SMN2LMNAKMT2ALRRK2 | |
| SCHEMBL22018586 | 0.79 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2LMNAKMT2ALRRK2 | |
| SCHEMBL22047016 | 0.78 | KMT2A (0.47) | ALDH1A1SMN1; SMN2LMNAKMT2ALRRK2 | |
| SCHEMBL22018968 | 0.77 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2LMNAKMT2ALRRK2 | |
| SCHEMBL13831508 | 0.68 | HPGD (0.34) | ALDH1A1SMN1; SMN2LMNAKMT2ACYP3A4 | |
| SCHEMBL13831500 | 0.68 | TP53 (0.55) | SMN1; SMN2LMNAKMT2AKDM4EMEN1 | |
| SCHEMBL22018976 | 0.68 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2LMNAKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2704575-B1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | UNIV VANDERBILT (US) | 2020-06-03 | — | — | EP | disclosed |
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |