Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22018537 | 0.84 | GPR119 (0.32) | ALDH1A1SMN1; SMN2GPR119KMT2AMEN1 | |
| SCHEMBL15983347 | 0.82 | TSHR (0.40) | ALDH1A1SMN1; SMN2LMNAKMT2APOLB | |
| SCHEMBL22018974 | 0.82 | TSHR (0.40) | ALDH1A1SMN1; SMN2LMNAKDM4EHPGD | |
| SCHEMBL13831472 | 0.81 | GPR119 (0.33) | ALDH1A1SMN1; SMN2GPR119 | |
| SCHEMBL22047017 | 0.80 | GPR119 (0.31) | ALDH1A1GPR119KMT2AMEN1POLB | |
| SCHEMBL18559190 | 0.80 | GPR119 (0.31) | GPR119 | |
| SCHEMBL13831477 | 0.78 | DGAT1 (0.35) | ALDH1A1SMN1; SMN2LMNAKDM4EKMT2A | |
| SCHEMBL13831449 | 0.77 | RECQL (0.34) | ALDH1A1SMN1; SMN2LMNAKDM4EGPR119 | |
| SCHEMBL22018967 | 0.77 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2LMNAKDM4EKMT2A | |
| SCHEMBL22018979 | 0.77 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2LMNAKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2704575-B1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | UNIV VANDERBILT (US) | 2020-06-03 | — | — | EP | disclosed |
| EP-3653054-A1 | COMPOSITION FOR INHIBITION OF INSECT SENSING | Vanderbilt University (US) | 2020-05-20 | — | — | EP | disclosed |