SCHEMBL22019143

CC[C@H](N)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	OPRD1	P41143	7/20	0.56

▸	GLP1R	P43220	1/20	0.52

▸	GCGR	P47871	1/20	0.52

▸	GIPR	P48546	1/20	0.52

▸	F2	P00734	3/20	0.51

▸	OPRM1	P35372	2/20	0.51

▸	OPRK1	P41145	2/20	0.51

▸	CALCR	P30988	2/20	0.51

▸	KEAP1	Q14145	2/20	0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30933098	0.93	REN (0.53)	OPRD1F2OPRM1OPRK1KEAP1
SCHEMBL30933101	0.91	REN (0.54)	OPRD1F2OPRM1OPRK1
SCHEMBL22380731	0.90	KDM1A (0.53)	OPRD1F2KEAP1
SCHEMBL22018606	0.89	OPRD1 (0.48)	OPRD1F2OPRM1OPRK1KEAP1
SCHEMBL30933102	0.89	NMUR2 (0.53)	OPRD1F2OPRM1OPRK1KEAP1
SCHEMBL29308367	0.87	BCL2L1 (0.48)	OPRD1GLP1RGIPRF2OPRM1
SCHEMBL30933097	0.87	APLNR (0.51)	OPRD1GLP1RGCGRGIPRF2
SCHEMBL29421924	0.87	APLNR (0.49)	OPRD1GLP1RGCGRGIPROPRM1
SCHEMBL31191391	0.87	OPRD1 (0.53)	OPRD1OPRM1OPRK1
SCHEMBL30933107	0.86	APLNR (0.51)	OPRD1GLP1RGCGRGIPROPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2020099925-A2	PEPTIDES AND PHARMACEUTICAL COMPOSITIONS FOR TREATING EYE DISEASES	YUYU PHARMA, INC. (KR)	2020-05-22	—	—	WO	disclosed