SCHEMBL29308367

SCHEMBL29308367

CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@@H]1C[C@@H](O)CN1)C(=O)N[C@@H](C)C(=O)NCC(=O)N1CCCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ BCL2L1 Q07817 1/20 0.48
▸ OPRD1 P41143 4/20 0.48
▸ OPRM1 P35372 3/20 0.48
▸ OPRK1 P41145 3/20 0.48
▸ KEAP1 Q14145 3/20 0.47
▸ F2 P00734 2/20 0.47
▸ GLP1R P43220 6/20 0.46
▸ GIPR P48546 6/20 0.46
▸ TFPI P10646 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22018606 0.98 OPRD1 (0.48) BCL2L1OPRD1OPRM1OPRK1KEAP1
SCHEMBL22018500 0.95 APLNR (0.49) OPRD1OPRM1OPRK1F2
SCHEMBL22018605 0.94 NPY2R (0.51) OPRD1OPRM1OPRK1F2TFPI
SCHEMBL25524956 0.94 NMUR2 (0.51) KEAP1F2TFPI
SCHEMBL22380728 0.94 APLNR (0.44) BCL2L1OPRD1OPRM1OPRK1GLP1R
SCHEMBL22018604 0.93 APLNR (0.45) OPRD1OPRM1OPRK1
SCHEMBL22018361 0.92 APLNR (0.46) OPRD1OPRM1OPRK1F2TFPI
SCHEMBL22018477 0.92 APLNR (0.46) OPRD1OPRM1OPRK1TFPI
SCHEMBL22922932 0.92 APLNR (0.46) OPRD1OPRM1OPRK1TFPI
SCHEMBL22018503 0.91 NTSR1 (0.51) OPRD1OPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037415-B2 Peptide and pharmaceutical composition for treating an eye disease comprising the same as an active pharmaceutical ingredient YUYU PHARMA, INC. (KR) 2024-07-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12037415-B2 Peptide and pharmaceutical composition for treating an eye disease comprising the same as an active pharmaceutical ingredient VIP, IAPP, NGLY1 BCL2L1 994/4885OPRD1 3752/4885OPRM1 4589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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