⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17753586 | 0.66 | — | — | |
| SCHEMBL20128636 | 0.66 | MAPT (0.39) | — | |
| SCHEMBL14570999 | 0.56 | TRIM24 (0.33) | — | |
| SCHEMBL28513579 | 0.55 | GSK3A (0.40) | — | |
| SCHEMBL29043805 | 0.54 | — | — | |
| SCHEMBL4438848 | 0.54 | — | — | |
| SCHEMBL9674642 | 0.54 | METAP2 (0.47) | — | |
| SCHEMBL12339195 | 0.54 | BMPR1B (0.36) | — | |
| SCHEMBL678602 | 0.53 | — | — | |
| SCHEMBL4538791 | 0.53 | S100A4 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200157078-A1 | NOVEL COMPOUNDS HAVING ESTROGEN RECEPTOR ALPHA DEGRADATION ACTIVITY AND USES THEREOF | ACCUTAR BIOTECHNOLOGY INC. (US) | 2020-05-21 | — | — | US | disclosed |