SCHEMBL22024142

SCHEMBL22024142

CCCCC(C)(CCC)C1CCCNC1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.33
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21191726 0.96 HTR2A (0.34) HTR2ACYP1A2
SCHEMBL18459246 0.95 HTR2A (0.32) HTR2A
SCHEMBL22023694 0.93 HTR2A (0.33) HTR2ACYP1A2
SCHEMBL22024127 0.93 HTR2A (0.33) HTR2A
SCHEMBL24736818 0.92 CCR2 (0.34) HTR2A
SCHEMBL26317203 0.92 CCR2 (0.34) HTR2A
SCHEMBL22141963 0.90 CCR2 (0.35) HTR2A
SCHEMBL22142074 0.90 CCR2 (0.35) HTR2A
SCHEMBL27293416 0.86 SSTR4 (0.34) CYP1A2
SCHEMBL25733300 0.84 GNAO1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230295113-A1 NLRP3 MODULATORS ZOMAGEN BIOSCIENCES LTD 2023-09-21 US disclosed
US-11198693-B2 Functionalized heterocycles as antiviral agents ENANTA PHARMACEUTICALS, INC. (US) 2021-12-14 US disclosed
US-20200165249-A1 FUNCTIONALIZED HETEROCYCLES AS ANTIVIRAL AGENTS ENANTA PHARMACEUTICALS, INC. 2020-05-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230295113-A1 NLRP3 MODULATORS NLRP3, NLRP1, NOD1 HTR2A 1815/4885CYP1A2 2072/4885
US-11198693-B2 Functionalized heterocycles as antiviral agents HCCS, HAVCR2, HDGF HTR2A 4389/4885CYP1A2 222/4885
US-20200165249-A1 FUNCTIONALIZED HETEROCYCLES AS ANTIVIRAL AGENTS HCCS, HAVCR2, HDGF HTR2A 4389/4885CYP1A2 222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.