SCHEMBL14415910

SCHEMBL14415910

CCC(C)(C)C1CCC(=O)N1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
SLC2A1 P11166 1/20 0.33
ALDH1A1 P00352 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CRBN Q96SW2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22023888 0.85 CRBN (0.32) LMNACRBN
SCHEMBL22024311 0.79 CRBN (0.31) LMNACRBN
SCHEMBL21565355 0.79 LMNA (0.33) LMNAALDH1A1SMN1; SMN2
SCHEMBL21191593 0.79 CCR2 (0.36) ALDH1A1CRBN
SCHEMBL7946755 0.79 ALDH1A1 (0.34) LMNAALDH1A1SMN1; SMN2CRBN
SCHEMBL14916972 0.79 ALDH1A1 (0.34) LMNAALDH1A1SMN1; SMN2CRBN
SCHEMBL11917928 0.79 ALDH1A1 (0.34) LMNAALDH1A1SMN1; SMN2CRBN
SCHEMBL20262367 0.78 ALDH1A1 (0.30) ALDH1A1SMN1; SMN2
SCHEMBL22024310 0.78 CRBN (0.33) LMNAALDH1A1SMN1; SMN2CRBN
SCHEMBL20804241 0.78 LMNA (0.33) LMNACRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11198693-B2 Functionalized heterocycles as antiviral agents ENANTA PHARMACEUTICALS, INC. (US) 2021-12-14 US disclosed
US-20210345611-A1 EXTENDED AND CONTINUOUS RELEASE COMPOSITIONS FOR PLANT HEALTH AND METHOD OF USE VERDESIAN LIFE SCIENCES U.S., LLC 2021-11-11 US disclosed
US-20200165249-A1 FUNCTIONALIZED HETEROCYCLES AS ANTIVIRAL AGENTS ENANTA PHARMACEUTICALS, INC. 2020-05-28 US disclosed
WO-2020046932-A1 EXTENDED AND CONTINUOUS RELEASE COMPOSITIONS FOR PLANT HEALTH AND METHODS OF USE VERDESIAN LIFE SCIENCES U.S., LLC (US) 2020-03-05 WO disclosed
US-7273885-B2 Inhibitors of serine proteases, particularly HCV NS3-NS4A protease VERTEX PHARMACEUTICALS INCORPORATED (US) 2007-09-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210345611-A1 EXTENDED AND CONTINUOUS RELEASE COMPOSITIONS FOR PLANT HEALTH AND METHOD OF USE APEH, GET3, NSF LMNA 2333/4885SLC2A1 74/4885ALDH1A1 2889/4885
US-11198693-B2 Functionalized heterocycles as antiviral agents HCCS, HAVCR2, HDGF LMNA 2656/4885SLC2A1 3821/4885ALDH1A1 2352/4885
US-20200165249-A1 FUNCTIONALIZED HETEROCYCLES AS ANTIVIRAL AGENTS HCCS, HAVCR2, HDGF LMNA 2656/4885SLC2A1 3821/4885ALDH1A1 2352/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.