SCHEMBL22025366

SCHEMBL22025366

c1ccc(C2=C(c3ccccc3)S(c3ccccc3)(c3ccccc3)C(c3ccccc3)=C2c2ccccc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
P2RX7 Q99572 1/20 0.33
PDE4B Q07343 1/20 0.32
MAPK1 P28482 2/20 0.32
KMT2A Q03164 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9351602 0.72 ALDH1A1 (0.40) ALDH1A1P2RX7PDE4BKMT2ANPC1
SCHEMBL1348770 0.72 ALDH1A1 (0.40) ALDH1A1PDE4BMAPK1KMT2ANPC1
SCHEMBL21299092 0.72 ALDH1A1 (0.40) ALDH1A1PDE4BMAPK1KMT2ANPC1
SCHEMBL24023668 0.72 ALDH1A1 (0.31) ALDH1A1
SCHEMBL852224 0.67 ALDH1A1 (0.67) ALDH1A1PDE4BMAPK1KMT2ANPC1
SCHEMBL532969 0.67 ALDH1A1 (0.67) ALDH1A1PDE4BMAPK1KMT2ANPC1
SCHEMBL532970 0.67 ALDH1A1 (0.67) ALDH1A1PDE4BMAPK1KMT2ANPC1
SCHEMBL23348635 0.67 CA12 (0.32) ALDH1A1
SCHEMBL20610837 0.67 ALDH1A1 (0.35) ALDH1A1PDE4BMAPK1KMT2ARAB9A
SCHEMBL8440556 0.65 ALDH1A1 (0.61) ALDH1A1P2RX7PDE4BMAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108917977-B The measuring method of the topology network architecture transition temperature of class glass polymer material 清华大学 2019-09-20 CN claimed
CN-109134891-A The preparation method of phenyl elastomer silicone 山东圣佑高科催化材料有限公司 2019-01-04 CN claimed
CN-108917977-A The measuring method of the topology network architecture transition temperature of class glass polymer material 清华大学 2018-11-30 CN claimed
CN-108587610-A A kind of aggregation-induced emission magnetic fluorescent coding microsphere, preparation method and applications 上海交通大学 2018-09-28 CN claimed
CN-108587609-A Nano-microsphere based on aggregation-induced emission material, preparation method and application 上海交通大学 2018-09-28 CN claimed
CN-104017129-B The fluorescent functional polymer nano-microspheres of a kind of temperature and pH double-response, preparation method and application JILIN UNIVERSITY (CN) 2016-03-02 CN claimed
CN-104004125-B A kind of two fluorescent functional polymer nano-microspheres of pH response and the application in tumor tissues detects thereof JILIN UNIVERSITY (CN) 2016-03-02 CN claimed
CN-104017129-A Fluorescence functional polymer nanometer microsphere with dual responsiveness to temperature and pH, preparing method and applications UNIV JILIN 2014-09-03 CN claimed
CN-104004125-A Dual-fluorescence functional polymer nanometer microsphere with pH response and application thereof in tumor tissue detection UNIV JILIN 2014-08-27 CN claimed
CN-102911386-B Fluorescent polymer brush film, preparation method of fluorescent polymer brush film and application of fluorescent polymer brush film in detecting explosives with high sensitivity UNIV JILIN 2014-05-07 CN claimed
CN-103288360-A Polymer molecule brush film with fluorescence/temperature intelligent responsiveness and preparation method thereof UNIV JILIN 2013-09-11 CN claimed
CN-102911386-A Fluorescent polymer brush film, preparation method of fluorescent polymer brush film and application of fluorescent polymer brush film in detecting explosives with high sensitivity UNIV JILIN 2013-02-06 CN claimed
CN-102115570-B Method for preparing nano fluorescence thermometer UNIV JILIN 2012-01-25 CN claimed
CN-102115570-A Method for preparing nano fluorescence thermometer UNIV JILIN 2011-07-06 CN claimed
US-11643729-B2 Perovskite film, method of preparing thereof, and optoelectronic device SHENZHEN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-05-09 US disclosed
US-20210355409-A1 PHOTOLUMINESCENT LUBRICATING GREASE COMPOSITION, PHOTOLUMINESCENT MATERIAL AND THE PREPARATION METHODS THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2021-11-18 US disclosed
US-20200165038-A1 TAMPER-EVIDENT MATERIALS, ADHESIVES, SEALS, AND CONTAINERS SUN CHEMICAL CORPORATION (US) 2020-05-28 US disclosed
CN-102115570-B Method for preparing nano fluorescence thermometer UNIV JILIN 2012-01-25 CN disclosed
CN-102300555-A Resuscitation fluid 2011-12-28 CN disclosed
CN-102115570-A Method for preparing nano fluorescence thermometer UNIV JILIN 2011-07-06 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210355409-A1 PHOTOLUMINESCENT LUBRICATING GREASE COMPOSITION, PHOTOLUMINESCENT MATERIAL AND THE PREPARATION METHODS THEREOF TPSD1, TPSG1, TPSB2 ALDH1A1 793/4885P2RX7 4768/4885PDE4B 4731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.