SCHEMBL9351602

SCHEMBL9351602

O=S1(=O)C(c2ccccc2)=C(c2ccccc2)C(c2ccccc2)=C1c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
P2RX7 Q99572 1/20 0.39
PDE4B Q07343 1/20 0.38
KMT2A Q03164 3/20 0.37
TDP1 Q9NUW8 1/20 0.37
CDC25A P30304 1/20 0.36
CDC25B P30305 1/20 0.36
MAPT P10636 4/20 0.36
LMNA P02545 3/20 0.36
HTT P42858 3/20 0.36
MEN1 O00255 1/20 0.36
NOX1 Q9Y5S8 1/20 0.36
GPR3 P46089 1/20 0.35
CA12 O43570 1/20 0.34
CA9 Q16790 1/20 0.34
GALR1 P47211 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
NPC1 O15118 1/20 0.34
PKM P14618 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9351626 0.87 CYP3A4 (0.54) ALDH1A1KMT2ATDP1MAPTLMNA
SCHEMBL8986271 0.86 ALDH1A1 (0.47) ALDH1A1KMT2ATDP1MAPTLMNA
SCHEMBL11659237 0.79 P2RX7 (0.43) ALDH1A1P2RX7KMT2ATDP1MAPT
SCHEMBL6308790 0.77 GPR3 (0.39) ALDH1A1KMT2AMAPTLMNAHTT
SCHEMBL10593881 0.75 CYP3A4 (0.46) ALDH1A1KMT2ATDP1MAPTLMNA
SCHEMBL3627652 0.74 BCL2L1 (0.42) ALDH1A1KMT2ATDP1MAPTLMNA
SCHEMBL1348770 0.74 ALDH1A1 (0.40) ALDH1A1PDE4BKMT2ATDP1MAPT
SCHEMBL21299092 0.74 ALDH1A1 (0.40) ALDH1A1PDE4BKMT2ACDC25ACDC25B
SCHEMBL11661835 0.73 ALDH1A1 (0.36) ALDH1A1KMT2ATDP1MAPTMEN1
SCHEMBL22025366 0.72 ALDH1A1 (0.38) ALDH1A1P2RX7PDE4BKMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1107267-A None JP disclosed
JP-4211266-A None JP disclosed
JP-1146878-A None JP disclosed
EP-0270685-B1 PHOTOSENSITIVE MATERIAL FOR ELECTROPHOTOGRAPHY MITSUI TOATSU CHEMICALS (JP) 1994-09-07 EP disclosed
JP-H04211266-A PHOTOSENSITIVE MATERIAL FOR ELECTRONIC PHOTOGRAPH MITSUI TOATSU CHEM INC 1992-08-03 JP disclosed
JP-H01146878-A PRODUCTION OF NITRO-SUBSTITUTED TETRAPHENYL-THIOPHENE-1,1-DIOXIDES MITSUI TOATSU CHEM INC 1989-06-08 JP disclosed
JP-H01107267-A ELECTROPHOTOGRAPHIC SENSITIVE BODY MITSUI TOATSU CHEM INC 1989-04-25 JP disclosed
US-4808503-A SENSITIVITY, DURABILITY MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1989-02-28 US disclosed
US-4808503-A SENSITIVITY, DURABILITY MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1989-02-28 US disclosed
EP-0270685-A1 PHOTOSENSITIVE MATERIAL FOR ELECTROPHOTOGRAPHY MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-06-15 EP disclosed
EP-0270685-A1 PHOTOSENSITIVE MATERIAL FOR ELECTROPHOTOGRAPHY MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-06-15 EP disclosed
WO-1987007736-A1 PHOTOSENSITIVE MATERIAL FOR ELECTROPHOTOGRAPHY MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1987-12-17 WO disclosed