Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | ULK1 | O75385 | 1/20 | 0.38 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22042603 | 0.76 | ALDH1A1 (0.49) | GAAMAPTRAB9AKDM4ENPC1 | |
| SCHEMBL22042452 | 0.76 | PDPK1 (0.47) | GAAMAPTRAB9AKDM4ENPC1 | |
| SCHEMBL6154131 | 0.76 | MAPT (0.74) | GAAMAPTRAB9AKDM4ENPC1 | |
| SCHEMBL5541098 | 0.76 | MTNR1B (0.58) | GAAMAPTRAB9AKDM4ENPC1 | |
| SCHEMBL4191925 | 0.75 | XDH (0.61) | GAAMAPTRAB9AKDM4ENPC1 | |
| SCHEMBL693394 | 0.74 | CYP1A1 (0.41) | TDP1CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL1569892 | 0.74 | CYP11B1 (0.57) | DYRK1AROCK2MAP4K4PRKACAROCK1 | |
| SCHEMBL22042677 | 0.73 | SLC22A12 (0.38) | GAAMAPTRAB9AKDM4ENPC1 | |
| SCHEMBL8312695 | 0.72 | ALDH1A1 (0.46) | KDM4ESLC22A12CHRNB2CHRNA4ULK1 | |
| SCHEMBL4185063 | 0.72 | ALPL (0.52) | KDM4ESLC22A12XDHMKNK2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020116662-A1 | CYCLOALKANE-1,3-DIAMINE DERIVATIVE | 第一三共株式会社 | 2020-06-11 | — | — | WO | disclosed |