Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP28 | Q96RU2 | 4/20 | 0.36 |
| ▸ | GPR6 | P46095 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | SMO | Q99835 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2204253 | 0.91 | PAX8 (0.41) | USP28GPR6RAB9APAX8HSP90AA1 | |
| SCHEMBL2206775 | 0.72 | MAPT (0.38) | GPR6RAB9ALMNAMAPTGAA | |
| SCHEMBL2204128 | 0.71 | LMNA (0.43) | USP28GPR6RAB9ALMNAMAPT | |
| SCHEMBL6557980 | 0.69 | LMNA (0.41) | USP28GPR6RAB9ALMNAMAPT | |
| SCHEMBL2207732 | 0.68 | USP28 (0.46) | USP28GPR6RAB9ALMNAMAPT | |
| SCHEMBL8489240 | 0.66 | GPR119 (0.38) | RAB9ALMNAMAPTGAACACNA1B | |
| SCHEMBL2206934 | 0.65 | MAPT (0.37) | USP28GPR6RAB9ALMNAMAPT | |
| SCHEMBL2203106 | 0.65 | MAPT (0.37) | USP28GPR6RAB9ALMNAMAPT | |
| SCHEMBL8673767 | 0.64 | POLB (0.39) | RAB9ALMNAMAPTGAACACNA1B | |
| SCHEMBL1063417 | 0.64 | KMT2A (0.52) | GPR6RAB9ALMNAMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1670772-B1 | DERIVATIVES OF 1,3-DIONES HAVING A HERBICIDAL ACTIVITY | ISAGRO RICERCA SRL (IT) | 2011-08-17 | — | — | EP | disclosed |
| US-7982047-B2 | Derivatives of 1,3-diones having a herbicidal activity | ISAGRO RICERCA S.R.L. (IT) | 2011-07-19 | — | — | US | disclosed |
| US-20070015918-A1 | Derivatives of 1,3-diones having a herbicidal activity | ISAGRO RICERCA S.R.L (IT) | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015918-A1 | Derivatives of 1,3-diones having a herbicidal activity | DDT, CYP1B1, CYP51A1 | USP28 1495/4885GPR6 4046/4885RAB9A 1773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.