Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22045489 | 0.86 | SYK (0.39) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL30046479 | 0.86 | SYK (0.39) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL22044745 | 0.84 | KCNH2 (0.35) | MEN1KMT2AMAPTGAAKCNH2 | |
| SCHEMBL30045875 | 0.84 | KCNH2 (0.35) | MEN1KMT2AMAPTGAAKCNH2 | |
| SCHEMBL21988960 | 0.82 | KMO (0.44) | MEN1KMT2AMAPTGAAKCNH2 | |
| SCHEMBL22046557 | 0.82 | KCNH2 (0.35) | MEN1KMT2AMAPTPOLBNPC1 | |
| SCHEMBL21988835 | 0.77 | KCNH2 (0.34) | MEN1KMT2AMAPTNPC1GAA | |
| SCHEMBL22044791 | 0.74 | ALDH1A1 (0.40) | MEN1KMT2AMAPTL3MBTL1RAB9A | |
| SCHEMBL22045556 | 0.73 | ALDH1A1 (0.39) | MEN1KMT2AL3MBTL1TSHRGAA | |
| SCHEMBL17665507 | 0.72 | MEN1 (0.58) | MEN1KMT2AMAPTPOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382892-A1 | Chemical Compounds | PFIZER INC. (US) | 2023-11-30 | — | — | US | disclosed |
| US-11702405-B2 | Chemical compounds | PFIZER INC. (US) | 2023-07-18 | — | — | US | disclosed |
| US-11014908-B2 | Chemical compounds | PFIZER INC. (US) | 2021-05-25 | — | — | US | disclosed |
| US-20200172512-A1 | Chemical Compounds | PFIZER INC. (US) | 2020-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200172512-A1 | Chemical Compounds | HBZ, HBB, HBS1L | MEN1 3178/4885KMT2A 3842/4885MAPT 305/4885 |
| US-11702405-B2 | Chemical compounds | HBZ, HBB, HBS1L | MEN1 3178/4885KMT2A 3842/4885MAPT 305/4885 |
| US-20230382892-A1 | Chemical Compounds | HBZ, HBB, HBS1L | MEN1 3178/4885KMT2A 3842/4885MAPT 305/4885 |
| US-11014908-B2 | Chemical compounds | HBZ, HBB, HBS1L | MEN1 3178/4885KMT2A 3842/4885MAPT 305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.