Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21989074 | 0.84 | PTGDR (0.48) | ALDH1A1TDP1L3MBTL1TBXAS1MCL1 | |
| SCHEMBL22044791 | 0.84 | ALDH1A1 (0.40) | ALDH1A1TDP1L3MBTL1TBXAS1PPARA | |
| SCHEMBL22044800 | 0.84 | PSEN1 (0.39) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL25807870 | 0.81 | ALDH1A1 (0.36) | ALDH1A1TDP1L3MBTL1TBXAS1MCL1 | |
| SCHEMBL22045493 | 0.77 | L3MBTL1 (0.37) | ALDH1A1TDP1L3MBTL1TBXAS1PPARA | |
| SCHEMBL25808017 | 0.75 | KCNH2 (0.41) | L3MBTL1KCNH2GAA | |
| SCHEMBL21988678 | 0.71 | MAPT (0.39) | ALDH1A1PPARAPPARGCYP2C8CYP2C9 | |
| SCHEMBL21989072 | 0.69 | MAPT (0.46) | ALDH1A1L3MBTL1CYP2C8CYP2C9KCNH2 | |
| SCHEMBL21988643 | 0.69 | MAPT (0.46) | ALDH1A1L3MBTL1CYP2C8CYP2C9KCNH2 | |
| SCHEMBL21988644 | 0.69 | MAPT (0.46) | ALDH1A1L3MBTL1CYP2C8CYP2C9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382892-A1 | Chemical Compounds | PFIZER INC. (US) | 2023-11-30 | — | — | US | disclosed |
| US-11702405-B2 | Chemical compounds | PFIZER INC. (US) | 2023-07-18 | — | — | US | disclosed |
| US-11014908-B2 | Chemical compounds | PFIZER INC. (US) | 2021-05-25 | — | — | US | disclosed |
| US-20200172512-A1 | Chemical Compounds | PFIZER INC. (US) | 2020-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200172512-A1 | Chemical Compounds | HBZ, HBB, HBS1L | ALDH1A1 1737/4885TDP1 1597/4885L3MBTL1 3751/4885 |
| US-11702405-B2 | Chemical compounds | HBZ, HBB, HBS1L | ALDH1A1 1737/4885TDP1 1597/4885L3MBTL1 3751/4885 |
| US-20230382892-A1 | Chemical Compounds | HBZ, HBB, HBS1L | ALDH1A1 1737/4885TDP1 1597/4885L3MBTL1 3751/4885 |
| US-11014908-B2 | Chemical compounds | HBZ, HBB, HBS1L | ALDH1A1 1737/4885TDP1 1597/4885L3MBTL1 3751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.