Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.58 |
| ▸ | TLR2 | O60603 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 7/20 | 0.55 |
| ▸ | MAOB | P27338 | 7/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10498103 | 0.98 | TSHR (0.59) | TLR4TLR2TSHRMAOAMAOB | |
| SCHEMBL7756955 | 0.98 | TSHR (0.59) | TLR4TLR2TSHRMAOAMAOB | |
| SCHEMBL584475 | 0.98 | TSHR (0.59) | TLR4TLR2TSHRMAOAMAOB | |
| SCHEMBL584671 | 0.98 | TSHR (0.59) | TLR4TLR2TSHRMAOAMAOB | |
| SCHEMBL3904389 | 0.98 | TSHR (0.59) | TLR4TLR2TSHRMAOAMAOB | |
| SCHEMBL8863665 | 0.98 | TSHR (0.59) | TLR4TLR2TSHRMAOAMAOB | |
| SCHEMBL6289516 | 0.98 | TSHR (0.59) | TLR4TLR2TSHRMAOAMAOB | |
| SCHEMBL10497495 | 0.98 | TSHR (0.59) | TLR4TLR2TSHRMAOAMAOB | |
| SCHEMBL10497968 | 0.98 | TSHR (0.59) | TLR4TLR2TSHRMAOAMAOB | |
| SCHEMBL8796357 | 0.98 | TSHR (0.59) | TLR4TLR2TSHRMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170348258-A1 | 3-Amino Benzamide Derivative Serving As B-Lactam Auxiliary Antibiotic, Preparation Method and Use Thereof | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2017-12-07 | — | — | US | claimed |
| CN-105461585-A | 3-aminobenzamide derivative as beta-lactam auxiliary antibiotic, preparation method and application | UNIV HONG KONG POLYTECHNIC | 2016-04-06 | — | — | CN | claimed |
| US-12029708-B2 | Alkoxy compounds for disease treatment | ACUCELA INC. (US) | 2024-07-09 | — | — | US | disclosed |
| US-12018228-B2 | Alkoxybenzaldehyde derivatives and precursors thereof | GIVAUDAN SA (CH) | 2024-06-25 | — | — | US | disclosed |
| CN-111511778-B | Water-absorbent resin and agricultural water-retaining material | 株式会社可乐丽 | 2023-11-21 | — | — | CN | disclosed |
| US-11787751-B2 | Water-absorbent resin and agricultural water-retaining material | KURARAY CO., LTD. (JP) | 2023-10-17 | — | — | US | disclosed |
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2023-07-13 | — | — | US | disclosed |
| US-11446261-B2 | Alkoxy compounds for disease treatment | ACUCELA INC. (US) | 2022-09-20 | — | — | US | disclosed |
| CN-114521105-A | Layered body for raising rice seedlings, blanket-shaped seedling, rice seedling box, and method for manufacturing rice seedling box | 株式会社可乐丽 | 2022-05-20 | — | — | CN | disclosed |
| US-20220002634-A1 | ALKOXYBENZALDEHYDE DERIVATIVES AND PRECURSORS THEREOF | GIVAUDAN SA (CH) | 2022-01-06 | — | — | US | disclosed |
| EP-3873880-A1 | ALKOXYBENZALDEHYDE DERIVATIVES AND PRECURSORS THEREOF | Givaudan SA (CH) | 2021-09-08 | — | — | EP | disclosed |
| EP-0255134-B1 | CARBOSTYRIL DERIVATIVES AND SALTS THEREOF, PROCESS FOR PREPARING THEM, AND CARDIOTONIC COMPOSITION CONTAINING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-03 | — | — | EP | disclosed |
| US-5162305-A | Calcium lowering in blood; hypoglycemic agents, analgesics | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| US-5071856-A | CARBOSTYRIL DERIVATIVES AND SALTS THEREOF | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-10 | — | — | US | disclosed |
| US-4886809-A | CARDIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-12-12 | — | — | US | disclosed |
| EP-0330241-A2 | Calcitonin derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-08-30 | — | — | EP | disclosed |
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |
| CN-1030415-A | Saturated heterocycle carboxamide derivatives and its preparation method | YAMANOUCHI PHARMA CO LTD (JP) | 1989-01-18 | — | — | CN | disclosed |
| EP-0255134-A2 | Carbostyril derivatives and salts thereof, process for preparing them, and cardiotonic composition containing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-02-03 | — | — | EP | disclosed |
| US-4085147-A | Preparation of meta-aryloxy-benzaldehydes | SHELL OIL COMPANY (US) | 1978-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12029708-B2 | Alkoxy compounds for disease treatment | ALDH1A2, CLN6, AGER | TLR4 595/4885TLR2 943/4885TSHR 2964/4885 |
| US-20170348258-A1 | 3-Amino Benzamide Derivative Serving As B-Lactam Auxiliary Antibiotic, Preparation Method and Use Thereof | BCAT2, SBDS, BCAT1 | TLR4 438/4885TLR2 163/4885TSHR 3829/4885 |
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | TLR4 517/4885TLR2 890/4885TSHR 2971/4885 |
| US-11446261-B2 | Alkoxy compounds for disease treatment | ALDH1A2, CLN6, AGER | TLR4 595/4885TLR2 943/4885TSHR 2964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.