Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 2/20 | 0.38 |
| ▸ | CASP2 | P42575 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 3/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22338310 | 0.87 | TSHR (0.45) | TSHRGBA1CASP2ALDH1A1HPGD | |
| SCHEMBL8975691 | 0.82 | LMNA (0.46) | TSHRCASP2ALDH1A1HPGDNAAA | |
| SCHEMBL1709958 | 0.81 | TSHR (0.53) | TSHRPKMALDH1A1HPGDMEN1 | |
| SCHEMBL14241913 | 0.79 | MEN1 (0.56) | TSHRPKMGBA1ALDH1A1HPGD | |
| SCHEMBL20048669 | 0.79 | FAAH (0.58) | CASP2ALDH1A1HPGDNAAAFAAH | |
| SCHEMBL11436700 | 0.78 | TSHR (0.50) | TSHRPKMGBA1ALDH1A1HPGD | |
| SCHEMBL10081169 | 0.78 | TSHR (0.60) | TSHRCASP2ALDH1A1HPGDMEN1 | |
| SCHEMBL18738990 | 0.77 | CASP2 (0.48) | TSHRCASP2ALDH1A1NAAAMEN1 | |
| SCHEMBL14002750 | 0.77 | ALDH1A1 (0.48) | TSHRCASP2ALDH1A1NAAAMEN1 | |
| SCHEMBL18648724 | 0.77 | TSHR (0.58) | TSHRALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020113209-A1 | PANTETHEINE DERIVATIVES AND USES THEREOF | COMET THERAPEUTICS, INC. (US) | 2020-06-04 | — | — | WO | disclosed |