SCHEMBL22063403

SCHEMBL22063403

c1cc(-c2c3ccccc3c(-c3ccc(-c4ccc5oc6c7ccccc7ccc6c5c4)cc3)c3ccccc23)cc(-c2cc3ccccc3c3ccccc23)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.37
MAPT P10636 3/20 0.37
HPGD P15428 3/20 0.37
TSHR P16473 3/20 0.37
HSD17B10 Q99714 3/20 0.37
ALDH1A1 P00352 2/20 0.37
ALOX15 P16050 1/20 0.37
CASP1 P29466 1/20 0.37
CASP7 P55210 1/20 0.37
CYP1A1 P04798 9/20 0.36
CYP1B1 Q16678 9/20 0.36
CYP1A2 P05177 8/20 0.36
PRKDC P78527 2/20 0.36
MAPK1 P28482 2/20 0.36
PDE5A O76074 1/20 0.36
TP53 P04637 1/20 0.36
ABCB1 P08183 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP19A1 P11511 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16067534 0.96 KDM4E (0.39) KDM4EMAPTHPGDTSHRHSD17B10
SCHEMBL16067709 0.92 KDM4E (0.39) KDM4EMAPTHPGDTSHRHSD17B10
SCHEMBL22063401 0.91 ALOX5 (0.40) KDM4EMAPTHPGDTSHRHSD17B10
SCHEMBL29295078 0.91 CYP1A1 (0.42) KDM4EMAPTHPGDTSHRHSD17B10
SCHEMBL22063355 0.91 CYP1A1 (0.44) KDM4EMAPTHPGDTSHRHSD17B10
SCHEMBL27335429 0.91 CYP1A1 (0.44) KDM4EMAPTHPGDTSHRHSD17B10
SCHEMBL24922853 0.89 CYP1A1 (0.43) KDM4EMAPTHPGDTSHRHSD17B10
SCHEMBL16067509 0.89 CYP1A1 (0.42) KDM4EMAPTHPGDTSHRHSD17B10
SCHEMBL16067595 0.89 CYP1A1 (0.45) KDM4EMAPTHPGDTSHRHSD17B10
SCHEMBL16067931 0.89 CYP1A1 (0.45) KDM4EMAPTHPGDTSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210320251-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPLIANCE IDEMITSU KOSAN CO.,LTD. (JP) 2021-10-14 US disclosed
US-20200212315-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, ELECTRONIC DEVICE, AND COMPOUND IDEMITSU KOSAN CO.,LTD. (JP) 2020-07-02 US disclosed
US-20200181160-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2020-06-11 US disclosed
US-20200185620-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2020-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210320251-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPLIANCE OLA1, TAS2R19, TMEM109 KDM4E 1466/4885MAPT 2477/4885HPGD 4701/4885
US-20200212315-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, ELECTRONIC DEVICE, AND COMPOUND OR10J3, ESR1, NFE2L2 KDM4E 2780/4885MAPT 3295/4885HPGD 3022/4885
US-20200181160-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE AHR, EMC2, NFE2L2 KDM4E 1043/4885MAPT 2800/4885HPGD 3497/4885
US-20200185620-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE EMC2, NFE2L2, AOC2 KDM4E 1152/4885MAPT 2667/4885HPGD 4021/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.