Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | RAF1 | P04049 | 2/20 | 0.49 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.48 |
| ▸ | PNLIP | P16233 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 3/20 | 0.46 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22069632 | 0.88 | PNLIP (0.51) | ALDH1A1MAPTFFAR1PNLIPMET | |
| SCHEMBL22114313 | 0.88 | MAPT (0.50) | ALDH1A1MAPTMEN1KMT2ARAF1 | |
| SCHEMBL22114364 | 0.86 | ALDH1A1 (0.48) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL22069654 | 0.86 | FFAR1 (0.52) | ALDH1A1MEN1KMT2AFFAR1PNLIP | |
| SCHEMBL22069709 | 0.85 | PNLIP (0.51) | MAPTMEN1KMT2APNLIP | |
| SCHEMBL22069696 | 0.85 | RNF4 (0.51) | ALDH1A1MAPTMEN1KMT2ARAF1 | |
| SCHEMBL22069658 | 0.84 | FFAR1 (0.55) | ALDH1A1MAPTMEN1KMT2ARAF1 | |
| SCHEMBL22069738 | 0.83 | HTR2A (0.49) | ALDH1A1FFAR1MET | |
| SCHEMBL22069685 | 0.83 | MET (0.46) | MAPTMEN1KMT2AFFAR1PNLIP | |
| SCHEMBL22069731 | 0.80 | P2RX4 (0.54) | FFAR1MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666769-A1 | NOVEL CASPASE INHIBITORS | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-06-17 | — | — | EP | disclosed |
| EP-3666769-A1 | NOVEL CASPASE INHIBITORS | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-06-17 | — | — | EP | disclosed |