Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 11/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.49 |
| ▸ | MET | P08581 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | PARG | Q86W56 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22069632 | 0.88 | PNLIP (0.51) | HTR2ASLC6A4KCNH2METFFAR1 | |
| SCHEMBL22069652 | 0.87 | MET (0.49) | HTR2ASLC6A4KCNH2METSCN9A | |
| SCHEMBL22069685 | 0.86 | MET (0.46) | METFFAR1PARGTSHR | |
| SCHEMBL22069731 | 0.85 | P2RX4 (0.54) | METFFAR1PARG | |
| SCHEMBL22069654 | 0.84 | FFAR1 (0.52) | METFFAR1PARGALDH1A1 | |
| SCHEMBL22069604 | 0.83 | ALDH1A1 (0.51) | METFFAR1ALDH1A1 | |
| SCHEMBL22069624 | 0.82 | MAPT (0.49) | FFAR1ALDH1A1TSHR | |
| SCHEMBL22069658 | 0.82 | FFAR1 (0.55) | METFFAR1ALDH1A1TSHR | |
| SCHEMBL22069626 | 0.81 | MAPT (0.47) | METFFAR1ALDH1A1TSHR | |
| SCHEMBL22069653 | 0.80 | L3MBTL1 (0.50) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666769-A1 | NOVEL CASPASE INHIBITORS | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-06-17 | — | — | EP | disclosed |
| EP-3666769-A1 | NOVEL CASPASE INHIBITORS | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-06-17 | — | — | EP | disclosed |