Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 13/20 | 0.54 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.48 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | PARG | Q86W56 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22069685 | 0.90 | MET (0.46) | P2RX4FFAR1METPARG | |
| SCHEMBL22069659 | 0.88 | P2RX4 (0.54) | P2RX4CYP2C8CYP2D6CYP2C9ADRA2B | |
| SCHEMBL22069611 | 0.87 | P2RX4 (0.57) | P2RX4CYP2C8CYP2D6CYP2C9ADRA2B | |
| SCHEMBL22069632 | 0.87 | PNLIP (0.51) | FFAR1METPARG | |
| SCHEMBL22069738 | 0.85 | HTR2A (0.49) | FFAR1METPARG | |
| SCHEMBL22069624 | 0.84 | MAPT (0.49) | FFAR1 | |
| SCHEMBL22069626 | 0.82 | MAPT (0.47) | FFAR1MET | |
| SCHEMBL22069658 | 0.81 | FFAR1 (0.55) | FFAR1MET | |
| SCHEMBL22069654 | 0.81 | FFAR1 (0.52) | FFAR1METPARG | |
| SCHEMBL22069604 | 0.80 | ALDH1A1 (0.51) | FFAR1MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666769-A1 | NOVEL CASPASE INHIBITORS | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-06-17 | — | — | EP | disclosed |
| EP-3666769-A1 | NOVEL CASPASE INHIBITORS | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-06-17 | — | — | EP | disclosed |