Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.53 |
| ▸ | MET | P08581 | 2/20 | 0.47 |
| ▸ | RAF1 | P04049 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RNF4 | P78317 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20679600 | 0.86 | SMN1; SMN2 (0.53) | FFAR1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL29965698 | 0.86 | SMN1; SMN2 (0.53) | FFAR1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL22069658 | 0.86 | FFAR1 (0.55) | FFAR1METRAF1MAPTKMT2A | |
| SCHEMBL22069703 | 0.86 | MET (0.48) | FFAR1METPOLBHTTKDM4E | |
| SCHEMBL22069580 | 0.83 | PNLIP (0.54) | FFAR1METMAPTPOLBHTT | |
| SCHEMBL22069579 | 0.82 | ALDH1A1 (0.49) | FFAR1METMAPTKMT2APOLB | |
| SCHEMBL22069696 | 0.82 | RNF4 (0.51) | FFAR1METRAF1MAPTKMT2A | |
| SCHEMBL22069558 | 0.81 | FFAR1 (0.50) | FFAR1METKMT2APOLBMEN1 | |
| SCHEMBL22069652 | 0.81 | MET (0.49) | FFAR1METPOLBHTTMITF | |
| SCHEMBL22069644 | 0.81 | ALDH1A1 (0.47) | FFAR1METMAPTKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666769-A1 | NOVEL CASPASE INHIBITORS | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-06-17 | — | — | EP | disclosed |
| EP-3666769-A1 | NOVEL CASPASE INHIBITORS | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-06-17 | — | — | EP | disclosed |