Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | PTGES | O14684 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31087520 | 1.00 | CYP3A4 (0.57) | CYP3A4PTGESMAPTALDH1A1POLB | |
| SCHEMBL22076265 | 0.90 | CYP3A4 (0.54) | CYP3A4PTGESMAPTALDH1A1POLB | |
| SCHEMBL22027571 | 0.88 | CYP3A4 (0.55) | CYP3A4PTGESMAPTALDH1A1POLB | |
| SCHEMBL22073603 | 0.88 | CYP3A4 (0.52) | CYP3A4PTGESMAPTALDH1A1POLB | |
| SCHEMBL31087515 | 0.88 | CYP3A4 (0.52) | CYP3A4PTGESMAPTALDH1A1POLB | |
| SCHEMBL6868015 | 0.85 | PTGES (0.68) | CYP3A4PTGESMAPTALDH1A1POLB | |
| SCHEMBL22027542 | 0.84 | CYP3A4 (0.63) | CYP3A4PTGESMAPTALDH1A1POLB | |
| SCHEMBL22073589 | 0.84 | CYP3A4 (0.60) | CYP3A4PTGESMAPTALDH1A1POLB | |
| Diethylamine SCHEMBL22229832 | 0.82 | PTGES (0.62) | CYP3A4PTGESMAPTALDH1A1POLB | |
| SCHEMBL22073613 | 0.81 | CYP3A4 (0.60) | CYP3A4PTGESMAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200179393-A1 | COMPOSITIONS AND METHODS FOR AMELIORATING PAIN | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2020-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200179393-A1 | COMPOSITIONS AND METHODS FOR AMELIORATING PAIN | ACHE, MPO, MMP8 | CYP3A4 4236/4885PTGES 38/4885MAPT 2162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.