Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.57 |
| ▸ | PPARD | Q03181 | 4/20 | 0.57 |
| ▸ | PPARA | Q07869 | 4/20 | 0.57 |
| ▸ | F7 | P08709 | 4/20 | 0.57 |
| ▸ | F3 | P13726 | 4/20 | 0.57 |
| ▸ | TERT | O14746 | 3/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | BLM | P54132 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | FABP4 | P15090 | 2/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.57 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.57 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.57 |
| ▸ | GMNN | O75496 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2208066 | 1.00 | PPARG (0.57) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL3338606 | 1.00 | PPARG (0.57) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL2208737 | 0.98 | PPARG (0.60) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL22555583 | 0.98 | PPARG (0.60) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL2206758 | 0.98 | PPARG (0.60) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL2206876 | 0.98 | PPARG (0.60) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL2206761 | 0.98 | PPARG (0.60) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL2208734 | 0.98 | PPARG (0.60) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL2206883 | 0.98 | PPARG (0.60) | PPARGPPARDPPARAF7F3 | |
| SCHEMBL2209155 | 0.94 | PPARG (0.52) | PPARGPPARDPPARAF7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117770450-B | High-purity capsaicin composition, and preparation method and application thereof | 天津福来特新材料科技有限公司 | 2024-06-21 | — | — | CN | claimed |
| EP-3094320-B1 | METHODS OF USING CAPSAICIN SYNTHASE FOR THE MICROBIAL PRODUCTION OF CAPSAICINOIDS | CONAGEN INC (US) | 2023-06-14 | — | — | EP | claimed |
| US-20230137573-A1 | Pharmaceutical Composition for Treating Cancer Comprising Trypsinogen and/or Chymotrypsinogen and an Active Agent Selected from a Selenium Compound, a Vanilloid Compound and a Cytoplasmic Glycolysis Reduction Agent | PROPANC PTY LTD (AU) | 2023-05-04 | — | — | US | claimed |
| US-11441162-B2 | Human gut microbiome-derived biosynthetic enzymes for production of fatty acid amides | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-09-13 | — | — | US | claimed |
| CN-106456588-B | Methods for the microbial production of capsaicinoids using capsaicin synthase | 科纳根公司 | 2021-04-30 | — | — | CN | claimed |
| US-20200299738-A1 | HUMAN GUT MICROBIOME-DERIVED BIOSYNTHETIC ENZYMES FOR PRODUCTION OF FATTY ACID AMIDES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-09-24 | — | — | US | claimed |
| WO-2020185627-A1 | HUMAN GUT MICROBIOME-DERIVED BIOSYNTHETIC ENZYMES FOR PRODUCTION OF FATTY ACID AMIDES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2020-09-17 | — | — | WO | claimed |
| US-10392643-B2 | Methods of using acyl-CoA synthetase for biosynthetic production of acyl-CoAs | CONAGEN INC. (US) | 2019-08-27 | — | — | US | claimed |
| CN-106419062-B | A kind of the automatic lifting adjustable-angle two sides table and its working method of control based on sensory | 徐州工程学院 | 2019-01-29 | — | — | CN | claimed |
| US-20190010522-A1 | METHODS OF MAKING CAPSINOIDS BY BIOSYNTHETIC PROCESSES | CONAGEN INC. (US) | 2019-01-10 | — | — | US | claimed |
| US-20070293703-A1 | Preparation and purification of synthetic capsaicin | ALGORX PHARMACEUTICALS, INC. (US) | 2007-12-20 | — | — | US | claimed |
| EP-1615880-A4 | PREPARATION AND PURIFICATION OF SYNTHETIC TRANS CAPSAICIN | ALGORX PHARMACEUTICALS INC (US) | 2007-03-07 | — | — | EP | claimed |
| CN-1865234-A | Capsicine chemical synthesis and purification method | INST OF BIOLOGY SHANDONG ACADE (CN) | 2006-11-22 | — | — | CN | claimed |
| CN-1852707-A | Preparation and purification of synthetic capsaicin | ALGORX (US) | 2006-10-25 | — | — | CN | claimed |
| CN-1791400-A | Composition for lowering lipid in body | AJINOMOTO KK (JP) | 2006-06-21 | — | — | CN | claimed |
| EP-1627634-A1 | COMPOSITION FOR LOWERING LIPID IN BODY | Ajinomoto Co., Inc. (JP) | 2006-02-22 | — | — | EP | claimed |
| EP-1615880-A2 | PREPARATION AND PURIFICATION OF SYNTHETIC CAPSAICIN | Algorx Pharmaceuticals, Inc. (US) | 2006-01-18 | — | — | EP | claimed |
| US-20050239883-A1 | Composition for lowering internal lipid content | AJINOMOTO CO., INC. (JP) | 2005-10-27 | — | — | US | claimed |
| US-20050085652-A1 | Preparation and purification of synthetic capsaicin | ALGORX PHARMACEUTICALS, INC. (US) | 2005-04-21 | — | — | US | claimed |
| WO-2004092122-A2 | PREPARATION AND PURIFICATION OF SYNTHETIC CAPSAICIN | ALGORX PHARMACEUTICALS, INC. (US) | 2004-10-28 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050085652-A1 | Preparation and purification of synthetic capsaicin | TRPV1, TRPV5, TAC3 | PPARG 2317/4885PPARD 2386/4885PPARA 2004/4885 |
| US-20190010522-A1 | METHODS OF MAKING CAPSINOIDS BY BIOSYNTHETIC PROCESSES | FADS2, COASY, FASN | PPARG 3404/4885PPARD 4130/4885PPARA 3390/4885 |
| US-20230137573-A1 | Pharmaceutical Composition for Treating Cancer Comprising Trypsinogen and/or Chymotrypsinogen and an Active Agent Selected from a Selenium Compound, a Vanilloid Compound and a Cytoplasmic Glycolysis Reduction Agent | SPINT2, PRSS1, SERPINB1 | PPARG 660/4885PPARD 731/4885PPARA 1439/4885 |
| US-20050239883-A1 | Composition for lowering internal lipid content | PNLIP, LIPC, LIPA | PPARG 574/4885PPARD 922/4885PPARA 376/4885 |
| US-20070293703-A1 | Preparation and purification of synthetic capsaicin | TRPV1, TRPV5, TAC3 | PPARG 2317/4885PPARD 2386/4885PPARA 2004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.