Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | F3 | P13726 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2208074 | 1.00 | MAPT (0.54) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL13781587 | 0.87 | ALDH1A1 (0.45) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL27463291 | 0.86 | CYP1A2 (0.46) | MAPTKMT2ALMNANPSR1CYP1A2 | |
| SCHEMBL438314 | 0.85 | MEN1 (0.70) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL3609468 | 0.85 | MAPT (0.58) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL3609471 | 0.85 | MAPT (0.58) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL10851473 | 0.84 | KMT2A (0.66) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL30553780 | 0.84 | KMT2A (0.66) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL10851464 | 0.84 | KMT2A (0.66) | MAPTMEN1KMT2ALMNANPSR1 | |
| SCHEMBL13916941 | 0.84 | MAPT (0.50) | MAPTMEN1KMT2ALMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109704926-B | Anticancer active molecular skeleton 1, 4-eneyne compound and preparation method and application thereof | 南京工业大学 | 2022-02-08 | — | — | CN | claimed |
| CN-109970560-A | Preparation method of tri-substituted 1, 3-diene compound | 南京工业大学 | 2019-07-05 | — | — | CN | claimed |
| CN-109704926-A | Anticancer active molecular skeleton 1, 4-eneyne compound and preparation method and application thereof | 南京工业大学 | 2019-05-03 | — | — | CN | claimed |
| CN-109704926-B | Anticancer active molecular skeleton 1, 4-eneyne compound and preparation method and application thereof | 南京工业大学 | 2022-02-08 | — | — | CN | disclosed |
| US-7982064-B2 | Method for preparing ortho-substituted aminoferrocenes | BROCK UNIVERSITY (CA) | 2011-07-19 | — | — | US | disclosed |
| US-20100137588-A1 | METHOD FOR PREPARING ORTHO-SUBSTITUTED AMINOFERROCENES | BROCK UNIVERSITY (CA) | 2010-06-03 | — | — | US | disclosed |
| US-4061771-A | Ethynylindenyl compounds and derivatives thereof used in the treatment of pain, fever and inflammation | WILLIAM H. RORER, INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-3983253-A | Ethynylindenyl compounds and derivatives thereof used in the treatment of pain, fever and inflammation | WILLIAM H. RORER, INC. (US) | 1976-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137588-A1 | METHOD FOR PREPARING ORTHO-SUBSTITUTED AMINOFERROCENES | LPO, AOC1, AOC2 | MAPT 4511/4885MEN1 2900/4885KMT2A 3110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.