SCHEMBL22081583

SCHEMBL22081583

C=C=Nc1c(Cl)cccc1Cl

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.38
CYP2A6 P11509 2/20 0.38
TSHR P16473 2/20 0.36
LMNA P02545 1/20 0.36
HTR3E A5X5Y0 1/20 0.32
HTR3B O95264 1/20 0.32
HTR3A P46098 1/20 0.32
HTR3D Q70Z44 1/20 0.32
HTR3C Q8WXA8 1/20 0.32
ALDH1A1 P00352 4/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
HSP90AA1 P07900 1/20 0.32
MAPT P10636 1/20 0.32
GABRA1 P14867 2/20 0.31
GABRB2 P47870 2/20 0.31
TAAR1 Q96RJ0 1/20 0.30
PNMT P11086 1/20 0.30
NR4A2 P43354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8734575 0.79 CYP1A2 (0.41) CYP1A2CYP2A6TSHRLMNAHTR3E
SCHEMBL326586 0.75 GABRA1 (0.56) CYP1A2CYP2A6TSHRLMNAHTR3E
SCHEMBL27988436 0.75 CYP1A2 (0.38) CYP1A2CYP2A6TSHRLMNAHTR3E
SCHEMBL894400 0.75 GABRA1 (0.54) CYP1A2CYP2A6TSHRLMNAHTR3E
SCHEMBL7644191 0.75 CYP1A2 (0.38) CYP1A2CYP2A6TSHRLMNAHTR3E
SCHEMBL11652732 0.71 CYP1A2 (0.35) CYP1A2CYP2A6TSHRLMNAHTR3E
SCHEMBL13770831 0.70 CYP1A2 (0.43) CYP1A2CYP2A6TSHRLMNAHTR3E
SCHEMBL4083032 0.69 CYP1A2 (0.47) CYP1A2CYP2A6TSHRLMNAHTR3E
SCHEMBL20049740 0.66 ALDH1A1 (0.32) CYP1A2CYP2A6ALDH1A1MEN1KMT2A
SCHEMBL3635498 0.65 GABRA1 (0.50) CYP1A2CYP2A6TSHRLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3662996-A2 MOLYBDENUM AND TUNGSTEN COMPLEXES AS OLEFIN METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS Verbio Vereinigte BioEnergie AG (DE) 2020-06-10 EP disclosed