Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.54 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.54 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17289579 | 0.87 | ALDH1A1 (0.47) | GABRA1GABRB2MIFCYP1A2ALDH1A1 | |
| SCHEMBL29812934 | 0.85 | GABRA1 (0.46) | GABRA1GABRB2MIFCYP1A2ALDH1A1 | |
| SCHEMBL158972 | 0.85 | GABRA1 (0.46) | GABRA1GABRB2MIFCYP1A2ALDH1A1 | |
| SCHEMBL1457069 | 0.85 | GABRA1 (0.50) | GABRA1GABRB2MIFCYP1A2ALDH1A1 | |
| SCHEMBL27596552 | 0.80 | GABRA1 (0.55) | GABRA1GABRB2MIFCYP1A2CYP3A4 | |
| SCHEMBL2305327 | 0.80 | GABRA1 (0.42) | GABRA1GABRB2MIFCYP1A2ALDH1A1 | |
| SCHEMBL8734575 | 0.79 | CYP1A2 (0.41) | GABRA1GABRB2CYP1A2ALDH1A1TDP1 | |
| SCHEMBL1457304 | 0.75 | ALDH1A1 (0.39) | GABRA1GABRB2MIFALDH1A1CYP3A4 | |
| SCHEMBL7644191 | 0.75 | CYP1A2 (0.38) | GABRA1GABRB2CYP1A2ALDH1A1TDP1 | |
| SCHEMBL22081583 | 0.75 | CYP1A2 (0.38) | GABRA1GABRB2CYP1A2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250084759-A1 | FLUORESCENT DYE OIL TRACER COMPOSITIONS | SAUDI ARABIAN OIL COMPANY (SA) | 2025-03-13 | — | — | US | claimed |
| US-20160250175-A1 | COMBINED APPLICATION OF ISOTHIOCYANATE COMPOUND AND ANTI-CANCER MEDICINE | JC (WUXI) COMPANY, INC. (CN) | 2016-09-01 | — | — | US | claimed |
| EP-3034076-A1 | COMBINED APPLICATION OF ISOTHIOCYANATE COMPOUND AND ANTI-CANCER MEDICINE | JC (Wuxi) COMPANY, Inc. (CN) | 2016-06-22 | — | — | EP | claimed |
| CN-103992265-B | Two three bromo 1,3-bis-pyridine alkali propane and preparation method thereof, using method, recovery method and application | XI'AN JIAOTONG UNIVERSITY (CN) | 2016-02-24 | — | — | CN | claimed |
| CN-103992265-A | Double tribromo 1,3-bipyridine onium salt dimethylmethane, and preparation method, application method, recovery method and application thereof | UNIV XI AN JIAOTONG | 2014-08-20 | — | — | CN | claimed |
| US-20250084759-A1 | FLUORESCENT DYE OIL TRACER COMPOSITIONS | SAUDI ARABIAN OIL COMPANY (SA) | 2025-03-13 | — | — | US | disclosed |
| EP-3446689-B1 | ISOTHIOCYANATE COMPOUND FOR USE IN THE TREATMENT OF HYPERBILIRUBINEMIA | JC WUXI COMPANY INC (CN) | 2025-01-08 | — | — | EP | disclosed |
| US-12188350-B2 | Fluorescent dye oil tracer compositions | SAUDI ARABIAN OIL COMPANY (SA) | 2025-01-07 | — | — | US | disclosed |
| EP-3541802-B1 | ALKYL SUBSTITUTED TRIAZOLE COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR | AMGEN INC (US) | 2025-01-01 | — | — | EP | disclosed |
| US-12071413-B2 | Azole derivatives as apelin receptor agonist | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-08-27 | — | — | US | disclosed |
| CN-117843611-A | Preparation and application of triazole antitumor inhibitor | 中国医学科学院药物研究所 | 2024-04-09 | — | — | CN | disclosed |
| US-20230399942-A1 | FLUORESCENT DYE OIL TRACER COMPOSITIONS | SAUDI ARABIAN OIL COMPANY (SA) | 2023-12-14 | — | — | US | disclosed |
| US-4244957-A | HYPOTENSIVE AGENTS | HOFFMAN-LA ROCHE INC. (US) | 1981-01-13 | — | — | US | disclosed |
| US-4169154-A | Method of treating depression with thiourea derivatives | HOFFMANN-LA ROCHE INC. (US) | 1979-09-25 | — | — | US | disclosed |
| EP-0002010-A1 | Derivatives of 2-imino-imidazolidine, processes for their preparation, pharmaceutical compositions containing them and intermediates | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1979-05-30 | — | — | EP | disclosed |
| US-4150138-A | Method of reducing blood pressure with thiourea derivatives and guanidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 1979-04-17 | — | — | US | disclosed |
| US-4113776-A | HYPOTENSIVE AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1978-09-12 | — | — | US | disclosed |
| US-4096276-A | Thiourea derivatives for treating hypertension | HOFFMANN-LA ROCHE INC. (US) | 1978-06-20 | — | — | US | disclosed |
| US-4089887-A | Process for the production of isothiocyanates | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DT) | 1978-05-16 | — | — | US | disclosed |
| US-4066695-A | ANTIHYPERTENSIVE AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1978-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160250175-A1 | COMBINED APPLICATION OF ISOTHIOCYANATE COMPOUND AND ANTI-CANCER MEDICINE | CHUK, KIT, MKI67 | GABRA1 3626/4885GABRB2 3271/4885MIF 986/4885 |
| US-12071413-B2 | Azole derivatives as apelin receptor agonist | APLNR, AGTR1, AGTR2 | GABRA1 2302/4885GABRB2 2704/4885MIF 3826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.