Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | TDO2 | P48775 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | AGER | Q15109 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22084443 | 0.86 | BACE1 (0.40) | IDO1MAPT | |
| SCHEMBL19249347 | 0.85 | ALDH1A1 (0.45) | MEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL19249331 | 0.81 | CYP1A2 (0.43) | IDO1TDO2MAPTKMT2A | |
| SCHEMBL19249090 | 0.72 | TDP1 (0.33) | — | |
| SCHEMBL22083949 | 0.72 | TAAR1 (0.35) | — | |
| SCHEMBL22084441 | 0.69 | POLB (0.48) | IDO1TDO2MEN1MAPTKMT2A | |
| SCHEMBL22083868 | 0.69 | CDK7 (0.34) | — | |
| SCHEMBL22083943 | 0.69 | OPRM1 (0.31) | IDO1TDO2MAPT | |
| SCHEMBL19249327 | 0.68 | IDO1 (0.33) | IDO1TDO2 | |
| SCHEMBL22083883 | 0.68 | RORC (0.40) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017133258-A1 | 1H-INDAZOLE DERIVATIVE AND USE THEREOF AS IDO INHIBITOR | 西华大学 | 2017-08-10 | — | — | WO | disclosed |