Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7015159 | 0.77 | CALM1 (0.50) | L3MBTL1HRH3TSHRLMNATAAR1 | |
| SCHEMBL1450103 | 0.75 | L3MBTL1 (0.50) | L3MBTL1HRH3HRH4MAPTSMN1; SMN2 | |
| SCHEMBL2750124 | 0.75 | L3MBTL1 (0.63) | L3MBTL1HRH3HRH4MAPTSMN1; SMN2 | |
| SCHEMBL29373231 | 0.74 | L3MBTL1 (0.68) | L3MBTL1HRH3HRH4MAPTSMN1; SMN2 | |
| SCHEMBL64435 | 0.74 | L3MBTL1 (0.68) | L3MBTL1HRH3HRH4MAPTSMN1; SMN2 | |
| SCHEMBL41191 | 0.73 | L3MBTL1 (0.59) | L3MBTL1HRH3HRH4MAPTSMN1; SMN2 | |
| SCHEMBL29830938 | 0.73 | L3MBTL1 (0.59) | L3MBTL1HRH3HRH4MAPTSMN1; SMN2 | |
| SCHEMBL31276017 | 0.72 | L3MBTL1 (0.66) | L3MBTL1HRH3HRH4HRH1LMNA | |
| Bromide SCHEMBL10759788 | 0.72 | L3MBTL1 (0.66) | L3MBTL1HRH3HRH4MAPTSMN1; SMN2 | |
| SCHEMBL31236458 | 0.72 | L3MBTL1 (0.66) | L3MBTL1HRH3HRH4MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220373541-A1 | Tri-functional Crosslinking Reagents | ETH ZURICH (CH) | 2022-11-24 | — | — | US | disclosed |
| US-11385225-B2 | Tri-functional crosslinking reagents | ETH ZURICH (CH) | 2022-07-12 | — | — | US | disclosed |
| EP-3374348-B1 | TRI-FUNCTIONAL CROSSLINKING REAGENTS | ETH ZUERICH (CH) | 2021-11-24 | — | — | EP | disclosed |
| US-10550093-B2 | Third generation taxoids and methods of using same | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2020-02-04 | — | — | US | disclosed |
| US-20180328922-A1 | TRI-FUNCTIONAL CROSSLINKING REAGENTS | ETH ZURICH (CH) | 2018-11-15 | — | — | US | disclosed |
| EP-3374348-A1 | TRI-FUNCTIONAL CROSSLINKING REAGENTS | ETH Zurich (CH) | 2018-09-19 | — | — | EP | disclosed |
| US-20180194744-A1 | Third Generation Taxoids and Methods of Using Same | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2018-07-12 | — | — | US | disclosed |
| EP-3316880-A1 | THIRD GENERATION TAXOIDS AND METHODS OF USING SAME | The Research Foundation for The State University of New York (US) | 2018-05-09 | — | — | EP | disclosed |
| US-9766235-B2 | Trifunctional crosslinking reagents | ETH ZURICH (CH) | 2017-09-19 | — | — | US | disclosed |
| WO-2017081069-A1 | TRI-FUNCTIONAL CROSSLINKING REAGENTS | ETH ZURICH (CH) | 2017-05-18 | — | — | WO | disclosed |
| WO-2017004478-A1 | THIRD GENERATION TAXOIDS AND METHODS OF USING SAME | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2017-01-05 | — | — | WO | disclosed |
| EP-2670755-B1 | TRIFUNCTIONAL CROSSLINKING REAGENTS | ETH ZUERICH (CH) | 2016-10-12 | — | — | EP | disclosed |
| EP-2942351-B1 | TRIFUNCTIONAL CROSSLINKING REAGENTS | ETH ZUERICH (CH) | 2016-10-12 | — | — | EP | disclosed |
| EP-2942351-A1 | TRIFUNCTIONAL CROSSLINKING REAGENTS | ETH Zurich (CH) | 2015-11-11 | — | — | EP | disclosed |
| US-20140011212-A1 | TRIFUNCTIONAL CROSSLINKING REAGENTS | ETH ZURICH (CH) | 2014-01-09 | — | — | US | disclosed |
| US-7981926-B2 | Fluorotaxoids | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2011-07-19 | — | — | US | disclosed |
| US-20090118355-A1 | Fluorotaxoids | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2009-05-07 | — | — | US | disclosed |
| WO-2008021242-A2 | FLUOROTAXOID-FATTY ACID CONJUGATES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2008-02-21 | — | — | WO | disclosed |
| WO-2007021957-A2 | FLUOROTAXOIDS | RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2007-02-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118355-A1 | Fluorotaxoids | FAU, ARF5, ARFGEF1 | L3MBTL1 1807/4885HRH3 4065/4885HRH4 3265/4885 |
| US-11385225-B2 | Tri-functional crosslinking reagents | ADGRF1, FCGR3B, FCGR2A | L3MBTL1 4372/4885HRH3 699/4885HRH4 475/4885 |
| US-20180194744-A1 | Third Generation Taxoids and Methods of Using Same | CBR3, TUBB3, CBX3 | L3MBTL1 3132/4885HRH3 1273/4885HRH4 1057/4885 |
| US-20220373541-A1 | Tri-functional Crosslinking Reagents | ADGRF1, SIGLEC7, ADGRE5 | L3MBTL1 4611/4885HRH3 1080/4885HRH4 1086/4885 |
| US-20180328922-A1 | TRI-FUNCTIONAL CROSSLINKING REAGENTS | ADGRF1, FCGR3B, FCGR2A | L3MBTL1 4372/4885HRH3 699/4885HRH4 475/4885 |
| US-10550093-B2 | Third generation taxoids and methods of using same | CBR3, TUBB3, CBX3 | L3MBTL1 3132/4885HRH3 1273/4885HRH4 1057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.