Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15416603 | 0.86 | ALDH1A1 (0.45) | CYP1A2MAOAERBB2FYNACHE | |
| SCHEMBL31741279 | 0.83 | HPRT1 (0.50) | CYP1A2MAOAERBB2FYNACHE | |
| SCHEMBL6201679 | 0.81 | CYP1A2 (0.46) | CYP1A2MAOAERBB2FYNACHE | |
| SCHEMBL22228583 | 0.77 | HPRT1 (0.52) | CYP1A2MAOAERBB2FYNACHE | |
| SCHEMBL1866520 | 0.77 | MTNR1A (0.48) | CYP1A2MAOAFYNAHRALDH1A1 | |
| SCHEMBL30423508 | 0.77 | MTNR1A (0.48) | CYP1A2MAOAFYNAHRALDH1A1 | |
| SCHEMBL1309270 | 0.75 | ALDH1A1 (0.50) | CYP1A2MAOAERBB2FYNACHE | |
| SCHEMBL6237203 | 0.74 | HPRT1 (0.58) | CYP1A2MAOAALDH1A1HSD17B10HIF1A | |
| SCHEMBL31275223 | 0.74 | HPRT1 (0.58) | CYP1A2MAOAALDH1A1HSD17B10HIF1A | |
| SCHEMBL11666288 | 0.74 | HSD17B10 (0.48) | CYP1A2MAOAALDH1A1HSD17B10HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1331 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12624048-B2 | Photochromic cyclic compound and curable composition containing the photochromic cyclic compound | TOKUYAMA CORPORATION (JP) | 2026-05-12 | — | — | US | claimed |
| EP-4313996-B1 | INDENONAPHTHOPYRANS HAVING TRIALKYLSILYL AND ETHYLENICALLY UNSATURATED GROUPS | TRANSITIONS OPTICAL LTD (IE) | 2026-05-06 | — | — | EP | claimed |
| EP-4713397-A1 | INDENONAPHTHOPYRANS HAVING PERFLUOROALKYL SUBSTITUTED ARYL / HETEROARYL SULFIDE AT POSITION-11 | Transitions Optical, Ltd. (IE) | 2026-03-25 | — | — | EP | claimed |
| US-20260070881-A1 | Photochromic Indeno-Fused Naphthopyran Compounds, Compositions, and Articles Containing Same | TRANSITIONS OPTICAL LTD (IE) | 2026-03-12 | — | — | US | claimed |
| EP-4581021-A1 | PHOTOCHROMIC INDENO-FUSED NAPHTHOPYRAN COMPOUNDS, COMPOSITIONS, AND ARTICLES CONTAINING SAME | Transitions Optical, Ltd. (IE) | 2025-07-09 | — | — | EP | claimed |
| CN-119816488-A | Photochromic indeno-fused naphthopyran compounds, compositions and articles containing the same | 全视线光学有限公司 | 2025-04-11 | — | — | CN | claimed |
| EP-4514597-A1 | METHOD FOR MAKING UV AND HEVL-ABSORBING OPHTHALMIC LENSES | Alcon Inc. (CH) | 2025-03-05 | — | — | EP | claimed |
| US-12222587-B2 | Method of producing a plastic lens having a coating layer | TOKUYAMA CORPORATION (JP) | 2025-02-11 | — | — | US | claimed |
| EP-4313567-B1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | ALCON INC (CH) | 2025-01-29 | — | — | EP | claimed |
| EP-4237232-B1 | METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES | ALCON INC (CH) | 2024-11-27 | — | — | EP | claimed |
| CN-1247604-A | Novel photochromic heterocyclic fused indenonaphthopyrans | PPG INDUSTRIES INC (US) | 2000-03-15 | — | — | CN | claimed |
| EP-0963390-A1 | PHOTOCHROMIC POLYURETHANE COATING AND ARTICLES HAVING SUCH A COATING | PPG Industries Ohio, Inc. (US) | 1999-12-15 | — | — | EP | claimed |
| EP-0958514-A1 | NOVEL PHOTOCHROMIC HETEROCYCLIC FUSED INDENONAPHTHOPYRANS | PPG Industries Ohio, Inc. (US) | 1999-11-24 | — | — | EP | claimed |
| CN-1226319-A | Novel photochemic heterocycllic fused indenonaphthopyrans | OPTICAL TRANSFORMING CO (US) | 1999-08-18 | — | — | CN | claimed |
| EP-0912908-A1 | NOVEL PHOTOCHROMIC HETEROCYCLIC FUSED INDENONAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 1999-05-06 | — | — | EP | claimed |
| WO-1998037115-A1 | PHOTOCHROMIC POLYURETHANE COATING AND ARTICLES HAVING SUCH A COATING | PPG INDUSTRIES OHIO, INC. (US) | 1998-08-27 | — | — | WO | claimed |
| WO-1998032037-A1 | NOVEL PHOTOCHROMIC HETEROCYCLIC FUSED INDENONAPHTHOPYRANS | PPG INDUSTRIES OHIO, INC. (US) | 1998-07-23 | — | — | WO | claimed |
| US-5723072-A | Photochromic heterocyclic fused indenonaphthopyrans | PPG INDUSTRIES, INC. (US) | 1998-03-03 | — | — | US | claimed |
| WO-1997048993-A1 | NOVEL PHOTOCHROMIC HETEROCYCLIC FUSED INDENONAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 1997-12-24 | — | — | WO | claimed |
| US-5698141-A | REVERSE CHARGE IN COLOR WHEN EXPOSURED TO ELECTROMAGNETIC RADIATION | PPG INDUSTRIES, INC. (US) | 1997-12-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260070881-A1 | Photochromic Indeno-Fused Naphthopyran Compounds, Compositions, and Articles Containing Same | CCND3, MRPS24, AP3S1 | CYP1A2 1960/4885MAOA 4702/4885ERBB2 3823/4885 |
| US-12624048-B2 | Photochromic cyclic compound and curable composition containing the photochromic cyclic compound | CCNL2, CRY2, CRY1 | CYP1A2 1295/4885MAOA 1373/4885ERBB2 878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.