SCHEMBL22091908

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22091860	0.89	MAPT (0.40)	TSHRLMNAPRNPALDH1A1L3MBTL1
	SCHEMBL22092127	0.88	ALDH1A1 (0.40)	TSHRPRNPALDH1A1MEN1KMT2A
	SCHEMBL22091798	0.87	TUBB4A (0.44)	TSHRLMNAPSEN1PSEN2APH1B
	SCHEMBL22091801	0.87	TSHR (0.49)	TSHRLMNAPRNPALDH1A1MEN1
	SCHEMBL22091789	0.85	CA2 (0.36)	LMNAALDH1A1L3MBTL1SMN1; SMN2PSEN1
	SCHEMBL22091783	0.84	ABCB11 (0.41)	TSHRLMNAPRNPALDH1A1MEN1
	SCHEMBL22091770	0.83	TSHR (0.41)	TSHRLMNAALDH1A1MEN1KMT2A
	SCHEMBL21883675	0.82	MAPT (0.47)	TSHRLMNAPRNPALDH1A1MEN1
	SCHEMBL15513563	0.79	KIF11 (0.45)	LMNAALDH1A1L3MBTL1SMN1; SMN2POLB
	SCHEMBL29636419	0.79	KIF11 (0.45)	LMNAALDH1A1L3MBTL1SMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.