Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.58 |
| ▸ | HTT | P42858 | 5/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | WDR5 | P61964 | 1/20 | 0.52 |
| ▸ | XBP1 | P17861 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14048137 | 0.78 | KMT2A (0.57) | LMNAHTTNPSR1MAPTTP53 | |
| SCHEMBL14048146 | 0.77 | KMT2A (0.56) | LMNAHTTMAPTTP53ALDH1A1 | |
| SCHEMBL14048147 | 0.76 | KMT2A (0.55) | LMNAHTTNPSR1MAPTTP53 | |
| SCHEMBL12407002 | 0.76 | MAPT (0.55) | LMNAMAPTTP53ALDH1A1KMT2A | |
| SCHEMBL12407072 | 0.76 | MAPT (0.54) | LMNAHTTMAPTTP53GAA | |
| SCHEMBL29562518 | 0.75 | MAPT (0.63) | LMNAHTTMAPTTP53GAA | |
| SCHEMBL29562355 | 0.75 | MAPT (0.63) | LMNAHTTNPSR1MAPTTP53 | |
| SCHEMBL2176669 | 0.75 | LMNA (0.61) | LMNAHTTNPSR1MAPTTP53 | |
| SCHEMBL16210882 | 0.75 | MEN1 (0.59) | MAPTTP53ALDH1A1KMT2AMAPK1 | |
| SCHEMBL2175966 | 0.72 | TSHR (0.72) | LMNAMAPTTP53ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10682359-B2 | Inhibitors of glucose kinases, along with methods of their formation and use | UNIVERSITY OF SOUTH CAROLINA (US) | 2020-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10682359-B2 | Inhibitors of glucose kinases, along with methods of their formation and use | GCK, GCKR, GALK1 | LMNA 3105/4885HTT 2743/4885NPSR1 2979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.