Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14048137 | 0.93 | KMT2A (0.57) | KMT2AMAPK1MEN1LMNASMN1; SMN2 | |
| SCHEMBL14048146 | 0.84 | KMT2A (0.56) | KMT2AMAPK1MEN1LMNASMN1; SMN2 | |
| SCHEMBL29562355 | 0.82 | MAPT (0.63) | KMT2AMAPK1MEN1LMNASMN1; SMN2 | |
| SCHEMBL29562518 | 0.82 | MAPT (0.63) | KMT2AMAPK1MEN1LMNASMN1; SMN2 | |
| SCHEMBL22095975 | 0.77 | PKM (0.61) | KMT2AMAPK1MEN1SMN1; SMN2MAPT | |
| SCHEMBL6187346 | 0.76 | HTR6 (0.74) | — | |
| SCHEMBL22095984 | 0.76 | LMNA (0.58) | KMT2AMAPK1MEN1LMNASMN1; SMN2 | |
| SCHEMBL29561286 | 0.76 | MAPT (0.55) | KMT2AMEN1LMNASMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL6188378 | 0.76 | HTR6 (0.73) | — | |
| SCHEMBL2176669 | 0.75 | LMNA (0.61) | KMT2AMEN1LMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008129288-A2 | DISULFONAMIDES USEFUL IN THE TREATMENT OF INFLAMMATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-10-30 | — | — | WO | disclosed |