Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | BRD2 | P25440 | 1/20 | 0.51 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14048147 | 0.93 | KMT2A (0.55) | KMT2AMAPK1MEN1TSHRNPC1 | |
| SCHEMBL14048146 | 0.86 | KMT2A (0.56) | KMT2AMAPK1MEN1TSHRLMNA | |
| SCHEMBL29562518 | 0.84 | MAPT (0.63) | KMT2AMAPK1MEN1TSHRLMNA | |
| SCHEMBL29562355 | 0.84 | MAPT (0.63) | KMT2AMAPK1MEN1TSHRLMNA | |
| SCHEMBL22095975 | 0.81 | PKM (0.61) | KMT2AMAPK1MEN1TSHRNPC1 | |
| SCHEMBL29561286 | 0.80 | MAPT (0.55) | KMT2AMEN1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL6187346 | 0.78 | HTR6 (0.74) | — | |
| SCHEMBL22095984 | 0.78 | LMNA (0.58) | KMT2AMAPK1MEN1LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6188378 | 0.78 | HTR6 (0.73) | — | |
| SCHEMBL2176669 | 0.77 | LMNA (0.61) | KMT2AMEN1TSHRLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008129288-A2 | DISULFONAMIDES USEFUL IN THE TREATMENT OF INFLAMMATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-10-30 | — | — | WO | disclosed |