Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25857082 | 0.85 | OPRM1 (0.48) | OPRM1OPRD1OPRK1ALDH1A1PKM | |
| SCHEMBL18641997 | 0.82 | OPRM1 (0.50) | OPRM1OPRD1OPRK1ALDH1A1PKM | |
| SCHEMBL28070639 | 0.78 | OPRM1 (0.46) | OPRM1OPRD1OPRK1ALDH1A1PKM | |
| SCHEMBL25857160 | 0.77 | ALDH1A1 (0.31) | ALDH1A1NPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL22863834 | 0.74 | OPRM1 (0.47) | OPRM1OPRD1OPRK1ALDH1A1ATM | |
| SCHEMBL18666981 | 0.74 | OPRM1 (0.47) | OPRM1OPRD1OPRK1ALDH1A1ATM | |
| SCHEMBL22100089 | 0.74 | OPRM1 (0.43) | OPRM1OPRD1OPRK1ALDH1A1PKM | |
| SCHEMBL13989231 | 0.74 | ALDH1A1 (0.50) | OPRM1OPRD1OPRK1ALDH1A1PKM | |
| SCHEMBL239348 | 0.74 | ALDH1A1 (0.50) | OPRM1OPRD1OPRK1ALDH1A1PKM | |
| SCHEMBL18127060 | 0.74 | ALDH1A1 (0.50) | OPRM1OPRD1OPRK1ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11801228-B2 | Modified guanidine-containing polymers for biologic delivery | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2023-10-31 | — | — | US | disclosed |
| US-20230225982-A1 | MODIFIED GUANIDINE-CONTAINING POLYMERS FOR BIOLOGIC DELIVERY | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2023-07-20 | — | — | US | disclosed |
| US-11529315-B1 | Modified guanidine-containing polymers for biologic delivery | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2022-12-20 | — | — | US | disclosed |
| US-10688189-B1 | Modulated guanidine-containing polymers or nanoparticles | THE FLORIDA INTERNATIONAL BOARD OF TRUSTEES (US) | 2020-06-23 | — | — | US | disclosed |
| US-20200188520-A1 | MODULATED GUANIDINE-CONTAINING POLYMERS OR NANOPARTICLES | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (US) | 2020-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230225982-A1 | MODIFIED GUANIDINE-CONTAINING POLYMERS FOR BIOLOGIC DELIVERY | GMPS, RNMT, GUCY1A1 | OPRM1 2522/4885OPRD1 3897/4885OPRK1 3789/4885 |
| US-10688189-B1 | Modulated guanidine-containing polymers or nanoparticles | RNMT, NAT10, GMPS | OPRM1 478/4885OPRD1 2498/4885OPRK1 1267/4885 |
| US-11801228-B2 | Modified guanidine-containing polymers for biologic delivery | GMPS, RNMT, GUCY1A1 | OPRM1 2522/4885OPRD1 3897/4885OPRK1 3789/4885 |
| US-20200188520-A1 | MODULATED GUANIDINE-CONTAINING POLYMERS OR NANOPARTICLES | RNMT, NAT10, GMPS | OPRM1 478/4885OPRD1 2498/4885OPRK1 1267/4885 |
| US-11529315-B1 | Modified guanidine-containing polymers for biologic delivery | GMPS, RNMT, GUCY1A1 | OPRM1 2522/4885OPRD1 3897/4885OPRK1 3789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.