Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 4/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3675681 | 0.75 | ALOX5 (0.57) | ALOX5GLAKMT2A | |
| SCHEMBL20226622 | 0.75 | USP2 (0.44) | BCHEACHEALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7999711 | 0.74 | ALOX5 (0.59) | ALOX5GLAKMT2A | |
| SCHEMBL30200719 | 0.74 | ALDH1A1 (0.49) | TBXAS1BCHEACHETDP1ALDH1A1 | |
| SCHEMBL1239542 | 0.72 | ALOX5 (0.65) | ALOX5ALDH1A1GLAKMT2A | |
| SCHEMBL11570899 | 0.72 | ALOX5 (0.45) | TBXAS1BCHEACHEALOX5ALDH1A1 | |
| SCHEMBL30200646 | 0.72 | ALDH1A1 (0.50) | BCHEACHETDP1ALDH1A1KMT2A | |
| SCHEMBL31301752 | 0.71 | ALOX15 (0.43) | TBXAS1ALDH1A1SMN1; SMN2ALOX15LTA4H | |
| SCHEMBL19474670 | 0.71 | LTA4H (0.53) | HTTSMN1; SMN2LTA4H | |
| SCHEMBL3379507 | 0.70 | HDAC8 (0.62) | ALDH1A1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020123850-A1 | FERROPORTIN INHIBITORS AND METHODS OF USE | GLOBAL BLOOD THERAPEUTICS, INC. (US) | 2020-06-18 | — | — | WO | disclosed |