Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
| ▸ | KCNJ5 | P48544 | 2/20 | 0.31 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22101905 | 0.88 | PDE2A (0.31) | KCNJ5KCNJ3RXFP1MAPTATM | |
| SCHEMBL22393766 | 0.85 | — | — | |
| SCHEMBL22101707 | 0.84 | ALDH1A1 (0.32) | RXFP1MAPK14LMNAMAPTL3MBTL1 | |
| SCHEMBL22101184 | 0.84 | CRHR1 (0.31) | LMNA | |
| SCHEMBL22393707 | 0.84 | MAPK3 (0.31) | — | |
| SCHEMBL22101713 | 0.82 | MAPT (0.34) | RXFP1HTTKMT2ALMNAMAPT | |
| SCHEMBL22101709 | 0.79 | GRIN1 (0.32) | RXFP1LMNA | |
| SCHEMBL22101536 | 0.78 | THRB (0.38) | P2RX7RXFP1HTTTHRBKMT2A | |
| SCHEMBL22101724 | 0.77 | KDM4E (0.45) | RXFP1KMT2ALMNAMAPT | |
| SCHEMBL22393702 | 0.77 | HCAR2 (0.32) | ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666772-A1 | DIARYLTHIOHYDANTOIN COMPOUND AS ANDROGEN RECEPTOR ANTAGONIST | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-06-17 | — | — | EP | disclosed |