SCHEMBL303525

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3378020	0.87	MEN1 (0.55)	KMT2AMEN1PRNPTHRBPOLB
	SCHEMBL304757	0.86	L3MBTL1 (0.50)	POLBPKMMAPTTP53USP2
	SCHEMBL303366	0.85	L3MBTL1 (0.56)	POLBPKMMAPTLMNATSHR
	SCHEMBL301844	0.83	KEAP1 (0.49)	KMT2AMEN1POLBPKMMAPT
	SCHEMBL3376941	0.81	POLB (0.49)	KMT2AMEN1PRNPTHRBPOLB
	SCHEMBL3377911	0.81	MAPT (0.54)	KMT2AMEN1MAPTTP53L3MBTL1
	SCHEMBL3380874	0.81	NR3C1 (0.54)	KMT2AMEN1MAPTTP53
	SCHEMBL303293	0.77	GAA (0.63)	KMT2AMEN1MAPTLMNA
	SCHEMBL302950	0.77	NR3C1 (0.55)	POLBMAPTTP53LMNA
	SCHEMBL302013	0.76	POLB (0.43)	KMT2AMEN1PRNPTHRBPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.