SCHEMBL302098

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3376229	0.90	ALDH1A1 (0.53)	KEAP1NFE2L2MAPTLMNAALDH1A1
	SCHEMBL302946	0.87	DAGLA (0.50)	MAPTLMNAALDH1A1PTGESALOX5
	SCHEMBL3380011	0.87	DAGLA (0.55)	MAPTLMNAALDH1A1
	SCHEMBL301844	0.86	KEAP1 (0.49)	KEAP1NFE2L2MAPTLMNAALDH1A1
	SCHEMBL3378121	0.83	MAPT (0.46)	MAPTLMNAALDH1A1KMT2AMEN1
	SCHEMBL302225	0.83	LMNA (0.60)	MAPTLMNAALDH1A1KMT2AMEN1
	SCHEMBL3378020	0.82	MEN1 (0.55)	MAPTLMNAALDH1A1KMT2AMEN1
	SCHEMBL302970	0.81	LMNA (0.59)	MAPTLMNAALDH1A1KMT2AMEN1
	SCHEMBL3376926	0.81	MAPT (0.60)	MAPTLMNAALDH1A1KMT2AMEN1
	SCHEMBL3379839	0.80	LMNA (0.56)	MAPTLMNAALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.