Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | LDHB | P07195 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 6/20 | 0.42 |
| ▸ | SYK | P43405 | 4/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29314116 | 0.86 | MET (0.41) | LDHALDHBMETSYKHDAC6 | |
| SCHEMBL22109393 | 0.81 | SYK (0.46) | LDHALDHBMETSYKATR | |
| SCHEMBL29315639 | 0.79 | LDHA (0.44) | LDHALDHBMETSYKATR | |
| SCHEMBL29314985 | 0.77 | MET (0.40) | LDHALDHBMETSYKHDAC6 | |
| SCHEMBL29314805 | 0.76 | LDHB (0.48) | LDHALDHBMETATRPDPK1 | |
| SCHEMBL22109397 | 0.76 | LDHA (0.48) | LDHALDHBMETSYKATR | |
| SCHEMBL29318098 | 0.76 | LDHA (0.42) | LDHALDHBMETSYKATR | |
| SCHEMBL1163132 | 0.74 | NPC1 (0.53) | METSYKHDAC6KLKB1KLK1 | |
| SCHEMBL22109324 | 0.74 | MET (0.70) | MET | |
| SCHEMBL29314182 | 0.73 | CSF1R (0.45) | LDHALDHBMET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3893872-B1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA INC (US) | 2024-07-17 | — | — | EP | disclosed |