Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAP1LC3B | Q9GZQ8 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21821819 | 0.86 | ALDH1A1 (0.41) | ALDH1A1KMT2AKDM4ETSHRMAPK1 | |
| SCHEMBL24379788 | 0.80 | SLC18A3 (0.45) | ALDH1A1KMT2ATSHRMAP1LC3BCYP2C19 | |
| SCHEMBL21821739 | 0.72 | MAP1LC3B (0.41) | ALDH1A1KMT2AKDM4ETSHRMAPK1 | |
| SCHEMBL22111791 | 0.72 | LMNA (0.39) | ALDH1A1KMT2AMTORPOLBHTR2A | |
| SCHEMBL21821650 | 0.72 | HSP90AA1 (0.37) | KDM4ETSHRPOLBMAP1LC3BCYP2C19 | |
| SCHEMBL22111786 | 0.72 | JAK1 (0.41) | — | |
| SCHEMBL22111797 | 0.69 | MAP1LC3B (0.40) | ALDH1A1KMT2AKDM4EMAP1LC3BCYP2C19 | |
| SCHEMBL22111781 | 0.68 | MAPK1 (0.40) | ALDH1A1KMT2AMAPK1DRD3 | |
| SCHEMBL21821929 | 0.67 | CYP3A4 (0.33) | ALDH1A1KMT2A | |
| SCHEMBL22111846 | 0.67 | MAP1LC3B (0.41) | ALDH1A1KMT2AKDM4ETSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11319303-B2 | Compound used as autophagy regulator, and preparation method therefor and uses thereof | Wigen Biomedicine Technology (shanghai) Co., Ltd. (CN) | 2022-05-03 | — | — | US | disclosed |
| US-20200190066-A1 | COMPOUND USED AS AUTOPHAGY REGULATOR, AND PREPARATION METHOD THEREFOR AND USES THEREOF | Wigen Biomedicine Technology (shanghai) Co., Ltd. (CN) | 2020-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11319303-B2 | Compound used as autophagy regulator, and preparation method therefor and uses thereof | ATG7, SQSTM1, BECN1 | ALDH1A1 4264/4885KMT2A 3378/4885KDM4E 2846/4885 |
| US-20200190066-A1 | COMPOUND USED AS AUTOPHAGY REGULATOR, AND PREPARATION METHOD THEREFOR AND USES THEREOF | ATG7, SQSTM1, BECN1 | ALDH1A1 4264/4885KMT2A 3378/4885KDM4E 2846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.