Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 4/20 | 0.46 |
| ▸ | MME | P08473 | 2/20 | 0.45 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.45 |
| ▸ | CHRND | Q07001 | 5/20 | 0.44 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.44 |
| ▸ | CHRNG | P07510 | 1/20 | 0.44 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8522310 | 0.87 | ACE (0.61) | ACEMMENAALAD2 | |
| SCHEMBL23835704 | 0.83 | MMP1 (0.52) | GRIA1CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL6859595 | 0.77 | CHRND (0.48) | GRIA1CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL9068704 | 0.74 | ACE (0.62) | ACEMMENAALAD2NPSR1 | |
| SCHEMBL4147877 | 0.73 | NAALAD2 (0.61) | ACEGRIA1MMENAALAD2 | |
| SCHEMBL4147882 | 0.73 | NAALAD2 (0.61) | ACEGRIA1MMENAALAD2 | |
| SCHEMBL29726740 | 0.73 | NAALAD2 (0.69) | ACEMMENAALAD2 | |
| SCHEMBL11277926 | 0.72 | CA2 (0.55) | ACEMME | |
| SCHEMBL18768260 | 0.72 | CTSG (0.42) | ACEGRIA1CHRNDCHRNA1CHRNG | |
| SCHEMBL4582092 | 0.72 | CHRND (0.60) | ACEGRIA1MMENAALAD2CHRND |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666258-A1 | METHOD OF TREATING PRADER-WILLI SYNDROME | Ferring BV (NL) | 2020-06-17 | — | — | EP | disclosed |