SCHEMBL22115384

SCHEMBL22115384

N#Cc1ccc(-c2ccc(-c3ccc(-c4ccc5ccc6cccnc6c5n4)c4ccccc34)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP1 P07148 1/20 0.47
CYP11B2 P19099 4/20 0.42
SLC40A1 Q9NP59 1/20 0.41
LMNA P02545 2/20 0.41
KDM4E B2RXH2 1/20 0.41
GMNN O75496 1/20 0.41
TP53 P04637 1/20 0.41
HSP90AA1 P07900 1/20 0.41
MMP2 P08253 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
MAPT P10636 1/20 0.41
MMP9 P14780 1/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
NFKB1 P19838 1/20 0.41
MMP8 P22894 1/20 0.41
CCR1 P32246 1/20 0.41
THPO P40225 1/20 0.41
MTOR P42345 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19939361 0.95 FABP1 (0.47) FABP1CYP11B2SLC40A1LMNAKDM4E
SCHEMBL19939363 0.94 FABP1 (0.47) FABP1CYP11B2SLC40A1LMNAKDM4E
SCHEMBL22115389 0.87 ALDH1A3 (0.45) CYP11B2LMNAKDM4ESMN1; SMN2ABCG2
SCHEMBL22065449 0.86 FABP1 (0.47) FABP1CYP11B2SLC40A1LMNAKDM4E
SCHEMBL17521977 0.86 LMNA (0.48) LMNAKDM4EGMNNTP53HSP90AA1
SCHEMBL22065162 0.85 FABP1 (0.46) FABP1CYP11B2SLC40A1LMNAKDM4E
SCHEMBL23954172 0.85 KDM4E (0.50) FABP1CYP11B2SLC40A1LMNAKDM4E
SCHEMBL22065452 0.85 FABP1 (0.47) FABP1CYP11B2SLC40A1LMNAKDM4E
SCHEMBL19939366 0.84 PDE4D (0.47) FABP1CYP11B2SLC40A1GLO1TDO2
SCHEMBL22065417 0.84 CYP11B2 (0.44) FABP1CYP11B2SLC40A1LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210210694-A1 ORGANIC LIGHT EMITTING DIODE LG CHEM, LTD. (KR) 2021-07-08 US disclosed
US-10950801-B2 Organic light-emitting device LG CHEM, LTD. (KR) 2021-03-16 US disclosed
EP-3754734-A1 ORGANIC LIGHT EMITTING DIODE LG CHEM, LTD. (KR) 2020-12-23 EP disclosed
US-20200287142-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM LTD. (KR) 2020-09-10 US disclosed
EP-3667749-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2020-06-17 EP disclosed