Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 4/20 | 0.47 |
| ▸ | PDE4A | P27815 | 2/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | FABP1 | P07148 | 1/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.40 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19939362 | 0.97 | PDE4D (0.48) | PDE4DPDE4APDE4CCLK4ALDH1A3 | |
| SCHEMBL19939361 | 0.89 | FABP1 (0.47) | PDE4DPDE4APDE4CALDH1A3CYP17A1 | |
| SCHEMBL23020058 | 0.88 | PDE4A (0.42) | PDE4DPDE4APDE4CCLK4ALDH1A3 | |
| SCHEMBL19939363 | 0.88 | FABP1 (0.47) | PDE4DPDE4APDE4CCYP17A1CYP11B1 | |
| SCHEMBL23020109 | 0.86 | ALDH1A3 (0.46) | CLK4ALDH1A3CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL22115384 | 0.84 | FABP1 (0.47) | CYP17A1CYP11B1CYP11B2TDO2FABP1 | |
| SCHEMBL23020108 | 0.82 | GRM5 (0.42) | GRM5 | |
| SCHEMBL21396159 | 0.82 | PGR (0.46) | PDE4DPDE4APDE4CCLK4CYP17A1 | |
| SCHEMBL20713520 | 0.82 | SLC40A1 (0.39) | PDE4DPDE4APDE4CCYP17A1CYP11B1 | |
| SCHEMBL15603719 | 0.82 | PGR (0.46) | PDE4DPDE4APDE4CCLK4CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180066180-A1 | ORGANIC LIGHT-EMITTING DEVICE | LG CHEM, LTD. (KR) | 2018-03-08 | — | — | US | disclosed |
| US-20180066180-A1 | ORGANIC LIGHT-EMITTING DEVICE | LG CHEM, LTD. (KR) | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180066180-A1 | ORGANIC LIGHT-EMITTING DEVICE | CRY1, CRY2, PPOX | PDE4D 4170/4885PDE4A 4438/4885PDE4C 4342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.