SCHEMBL22116201

SCHEMBL22116201

Cc1ccc(CC(CCl)N/C(=N/O)c2cc(Cl)nnc2Oc2cccc(C(F)(F)F)c2)c(C)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RY1 P47900 4/20 0.34
PTGER4 P35408 1/20 0.34
NPSR1 Q6W5P4 3/20 0.34
ALDH1A1 P00352 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
MCOLN3 Q8TDD5 1/20 0.34
KDM4E B2RXH2 4/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2C19 P33261 2/20 0.33
CYP2C9 P11712 1/20 0.33
RECQL P46063 1/20 0.33
HTT P42858 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MAPT P10636 2/20 0.32
RAB9A P51151 2/20 0.32
F10 P00742 1/20 0.32
ADORA2A P29274 1/20 0.32
LMNA P02545 1/20 0.31
CCR2 P41597 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22116206 1.00 P2RY1 (0.34) P2RY1PTGER4NPSR1ALDH1A1MEN1
SCHEMBL30308995 0.89 PTGER4 (0.43) P2RY1PTGER4NPSR1ALDH1A1MEN1
SCHEMBL22116017 0.89 PTGER4 (0.43) P2RY1PTGER4NPSR1ALDH1A1MEN1
SCHEMBL22116204 0.84 P2RY1 (0.34) P2RY1PTGER4NPSR1ALDH1A1MEN1
SCHEMBL22116047 0.81 PTGER4 (0.42) P2RY1PTGER4NPSR1ALDH1A1MEN1
SCHEMBL30308953 0.81 PTGER4 (0.42) P2RY1PTGER4NPSR1ALDH1A1MEN1
SCHEMBL30284472 0.77 MAPT (0.32) PTGER4CYP1A2CYP2C19CYP2C9MAPT
SCHEMBL29006588 0.76 RAB9A (0.38) P2RY1PTGER4ALDH1A1CYP1A2CYP2C19
SCHEMBL30254886 0.76 RAB9A (0.38) P2RY1PTGER4ALDH1A1CYP1A2CYP2C19
SCHEMBL22115997 0.76 PTGER4 (0.40) P2RY1PTGER4NPSR1ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137083-A1 HETEROCYCLYL PYRIDAZINE AS FUNGICIDAL COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 2026-05-21 US disclosed
US-12501900-B2 Heterocyclyl pyridazine as fungicidal compounds BAYER AKTIENGESELLSCHAFT (DE) 2025-12-23 US disclosed
US-20240016152-A1 ACTIVE COMPOUND COMBINATIONS BAYER AKTIENGESELLSCHAFT (DE) 2024-01-18 US disclosed
EP-4167740-A1 ACTIVE COMPOUND COMBINATIONS Bayer Aktiengesellschaft (DE) 2023-04-26 EP disclosed
US-20230064576-A1 HETEROCYCLYL PYRIDAZINE AS FUNGICIDAL COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 2023-03-02 US disclosed
WO-2021255070-A1 ACTIVE COMPOUND COMBINATIONS BAYER AKTIENGESELLSCHAFT (DE) 2021-12-23 WO disclosed
EP-3898620-A1 HETEROCYCLYL PYRIDAZINE AS FUNGICIDAL COMPOUNDS Bayer Aktiengesellschaft (DE) 2021-10-27 EP disclosed
WO-2020127780-A1 HETEROCYCLYL PYRIDAZINE AS FUNGICIDAL COMPOUNDS BAYER AKTIENGESELLSCHAFT (DE) 2020-06-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240016152-A1 ACTIVE COMPOUND COMBINATIONS CYP51A1, ERG28, BROX P2RY1 2122/4885PTGER4 4278/4885NPSR1 4478/4885
US-20230064576-A1 HETEROCYCLYL PYRIDAZINE AS FUNGICIDAL COMPOUNDS PNPO, PDXK, BLVRB P2RY1 1127/4885PTGER4 4411/4885NPSR1 4520/4885
US-12501900-B2 Heterocyclyl pyridazine as fungicidal compounds PNPO, PDXK, BLVRB P2RY1 1127/4885PTGER4 4411/4885NPSR1 4520/4885
US-20260137083-A1 HETEROCYCLYL PYRIDAZINE AS FUNGICIDAL COMPOUNDS CBR1, CBR3, CYC1 P2RY1 1006/4885PTGER4 4546/4885NPSR1 1519/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.