Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.42 |
| ▸ | NPY4R | P50391 | 3/20 | 0.37 |
| ▸ | NPY1R | P25929 | 2/20 | 0.37 |
| ▸ | NPY2R | P49146 | 2/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22117392 | 1.00 | SIRT5 (0.42) | SIRT5NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL22117487 | 0.86 | NPY4R (0.52) | SIRT5NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL22117485 | 0.86 | NPY4R (0.52) | SIRT5NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL22117537 | 0.82 | NPY4R (0.53) | NPY4RNPY1RNPY2RNPY5RPTPN2 | |
| SCHEMBL22117535 | 0.82 | NPY4R (0.53) | NPY4RNPY1RNPY2RNPY5RPTPN2 | |
| SCHEMBL31679015 | 0.81 | CTSL (0.55) | — | |
| SCHEMBL22117586 | 0.81 | KISS1R (0.51) | NPY4RNPY1RNPY2RNPY5RPTPN2 | |
| SCHEMBL22117585 | 0.81 | KISS1R (0.51) | NPY4RNPY1RNPY2RNPY5RPTPN2 | |
| SCHEMBL28637145 | 0.81 | CTSL (0.36) | SIRT5NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL28637147 | 0.81 | CTSL (0.36) | SIRT5NPY4RNPY1RNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898652-A1 | MITOCHONDRIA-TARGETING PEPTIDES | Stealth Biotherapeutics Corp (MC) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020131282-A1 | MITOCHONDRIA-TARGETING PEPTIDES | STEALTH BIOTHERAPEUTICS CORP. (MC) | 2020-06-25 | — | — | WO | disclosed |