Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | CTSC | P53634 | 1/20 | 0.48 |
| ▸ | NPY4R | P50391 | 3/20 | 0.46 |
| ▸ | NPY1R | P25929 | 2/20 | 0.46 |
| ▸ | NPY2R | P49146 | 2/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22117585 | 1.00 | KISS1R (0.51) | KISS1RCTSLPTPN2PTPN1CTSC | |
| SCHEMBL7785244 | 0.87 | NPY4R (0.56) | KISS1RCTSLCTSCNPY4RNPY1R | |
| SCHEMBL17073781 | 0.87 | CTSL (0.63) | CTSLSIRT2 | |
| SCHEMBL6431108 | 0.86 | MMP2 (0.56) | CTSLCTSC | |
| SCHEMBL28323436 | 0.86 | MMP2 (0.56) | CTSLCTSC | |
| SCHEMBL30688828 | 0.86 | MMP2 (0.56) | CTSLCTSC | |
| SCHEMBL22117384 | 0.86 | NPY4R (0.64) | KISS1RCTSLPTPN2PTPN1NPY4R | |
| SCHEMBL22117385 | 0.86 | NPY4R (0.64) | KISS1RCTSLPTPN2PTPN1NPY4R | |
| SCHEMBL17553458 | 0.85 | PAX8 (0.52) | KISS1RCTSLPTPN2PTPN1SIRT2 | |
| SCHEMBL29540489 | 0.85 | CTSL (0.54) | CTSLCTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898652-A1 | MITOCHONDRIA-TARGETING PEPTIDES | Stealth Biotherapeutics Corp (MC) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020131282-A1 | MITOCHONDRIA-TARGETING PEPTIDES | STEALTH BIOTHERAPEUTICS CORP. (MC) | 2020-06-25 | — | — | WO | disclosed |