SCHEMBL22117540

SCHEMBL22117540

N=C(N)NCCC[C@@H](NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](CC1CCOCC1)C(=O)N[C@@H](CCCCNC(=O)O)C(N)=O

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 12/20 0.47
▸ NPY1R P25929 7/20 0.47
▸ NPY2R P49146 5/20 0.47
▸ NPY5R Q15761 5/20 0.47
▸ KISS1R Q969F8 4/20 0.45
▸ F2R P25116 2/20 0.43
▸ OPRM1 P35372 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22117542 1.00 NPY4R (0.47) NPY4RNPY1RNPY2RNPY5RKISS1R
SCHEMBL22117841 0.94 NPY4R (0.47) NPY4RNPY1RNPY2RNPY5RKISS1R
SCHEMBL22117843 0.94 NPY4R (0.47) NPY4RNPY1RNPY2RNPY5RKISS1R
SCHEMBL31679033 0.92 CTSL (0.48) NPY4RNPY1RNPY2RNPY5RKISS1R
SCHEMBL22117544 0.87 NPY4R (0.50) NPY4RNPY1RNPY2RNPY5RKISS1R
SCHEMBL22117546 0.87 NPY4R (0.50) NPY4RNPY1RNPY2RNPY5RKISS1R
SCHEMBL28645296 0.86 OPRM1 (0.43) NPY4RNPY1RNPY2RNPY5ROPRM1
SCHEMBL28645300 0.86 OPRM1 (0.43) NPY4RNPY1RNPY2RNPY5ROPRM1
SCHEMBL22117404 0.86 KISS1R (0.51) NPY4RNPY1RNPY2RNPY5RKISS1R
SCHEMBL22117405 0.86 KISS1R (0.51) NPY4RNPY1RNPY2RNPY5RKISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3898652-A1 MITOCHONDRIA-TARGETING PEPTIDES Stealth Biotherapeutics Corp (MC) 2021-10-27 — — EP disclosed
WO-2020131282-A1 MITOCHONDRIA-TARGETING PEPTIDES STEALTH BIOTHERAPEUTICS CORP. (MC) 2020-06-25 — — WO disclosed
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