Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15901985 | 0.81 | ALDH1A1 (0.36) | NOTUMTDP1ALDH1A1POLB | |
| SCHEMBL30682543 | 0.79 | HTR6 (0.39) | NOTUMPOLBL3MBTL1 | |
| SCHEMBL22154471 | 0.79 | HTR6 (0.39) | NOTUMPOLBL3MBTL1 | |
| SCHEMBL22126555 | 0.76 | AKR1C3 (0.37) | NOTUM | |
| SCHEMBL20503064 | 0.72 | CYP2A6 (0.41) | TDP1ALDH1A1POLBAPEX1CTDSP1 | |
| SCHEMBL249819 | 0.72 | ALDH1A1 (0.33) | TDP1ALDH1A1POLBAPEX1CTDSP1 | |
| SCHEMBL1229812 | 0.72 | ERN1 (0.42) | ALDH1A1 | |
| SCHEMBL15901961 | 0.72 | ERN1 (0.42) | TDP1ALDH1A1POLB | |
| SCHEMBL28489297 | 0.71 | PTGS2 (0.43) | ALDH1A1L3MBTL1 | |
| SCHEMBL28507087 | 0.71 | PTGS2 (0.46) | ALDH1A1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3596089-B1 | ANTIBACTERIAL COMPOUNDS | UNIV NOTTINGHAM (GB) | 2023-12-06 | — | — | EP | disclosed |
| US-11192888-B2 | Antibacterial compounds | THE UNIVERSITY OF NOTTINGHAM (GB) | 2021-12-07 | — | — | US | disclosed |
| US-20200199118-A1 | ANTIBACTERIAL COMPOUNDS | THE UNIVERSITY OF NOTTINGHAM (GB) | 2020-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11192888-B2 | Antibacterial compounds | CFTR, CLPP, MRPL21 | NOTUM 2477/4885TDP1 4659/4885NSD2 4079/4885 |
| US-20200199118-A1 | ANTIBACTERIAL COMPOUNDS | CFTR, CLPP, MRPL21 | NOTUM 2477/4885TDP1 4659/4885NSD2 4079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.