Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12186137 | 0.85 | TSHR (0.33) | BCHECES1KDM1AKDM1BMEN1 | |
| SCHEMBL24357635 | 0.81 | KDM1A (0.32) | KDM1AKDM1BALDH1A1CYP1A2ALOX15 | |
| SCHEMBL17645789 | 0.79 | ALDH1A1 (0.34) | KDM1AKDM1BALDH1A1CYP1A2ALOX15 | |
| SCHEMBL29545648 | 0.79 | SHBG (0.34) | KDM1AKDM1BMEN1NPC1MAPT | |
| SCHEMBL22128456 | 0.79 | SHBG (0.34) | KDM1AKDM1BMEN1NPC1MAPT | |
| SCHEMBL30027997 | 0.77 | AGBL2 (0.40) | ALOX15GPR27 | |
| SCHEMBL31672222 | 0.77 | PGK1 (0.32) | GPR27 | |
| SCHEMBL17847021 | 0.77 | AGBL2 (0.40) | ALOX15GPR27 | |
| SCHEMBL15706607 | 0.77 | TSHR (0.33) | BCHECES1KDM1AKDM1BMEN1 | |
| SCHEMBL22830380 | 0.75 | CSNK2A1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11407725-B2 | Selective fluorescent probe for aldehyde dehydrogenase | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2022-08-09 | — | — | US | disclosed |
| US-20200199092-A1 | SELECTIVE FLUORESCENT PROBE FOR ALDEHYDE DEHYDROGENASE | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2020-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11407725-B2 | Selective fluorescent probe for aldehyde dehydrogenase | ALDH1A1, ALDH3A1, ALDH16A1 | BCHE 1888/4885CES1 114/4885KDM1A 399/4885 |
| US-20200199092-A1 | SELECTIVE FLUORESCENT PROBE FOR ALDEHYDE DEHYDROGENASE | ALDH1A1, ALDH3A1, ALDH16A1 | BCHE 1888/4885CES1 114/4885KDM1A 399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.